Patch test triggering recurrence of distant dermatitis: the flare-up phenomenon

Daniele Torchia; Chiara Capretti; Benedetto Pizzo; Stefano Francalanci
August 2008
CMAJ: Canadian Medical Association Journal;8/12/2008, Vol. 179 Issue 4, p341
Academic Journal
The article focuses on the patch test conducted to a 37-year-old woman with pruritic, vesiculobullous eruption on her neck caused by a suspected acute allergic contact dermatitis. The test was performed on her back using scrapings from the ebony pendant. Rashes resembling the shape of the pendant was developed on the region where the test was conducted. It proved that the presence of macassar quinone, the only known allergen of the ebony was the cause of allergic contact dermatitis. Once the allergen penetrated the skin and entered the blood stream, it could reactivate specific memory T cells resulting to skin inflammation.


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