TITLE

Solitary Fibrous Tumor of the Pleura: An Analysis of 13 Cases

AUTHOR(S)
Chunlai Lu; Yuan Ji; Fei Shan; Weigang Guo; Jianyong Ding; Di Ge
PUB. DATE
August 2008
SOURCE
World Journal of Surgery;Aug2008, Vol. 32 Issue 8, p1663
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Solitary fibrous tumor of the pleura is a rare soft-tissue tumor. In search of appropriate diagnosis and treatment methods, we present our experience with 13 patients. The medical charts of 13 patients treated during the last 5 years were reviewed, as well as pathological records, including immunohistochemical stains. Follow-up data were obtained. In addition, a literature review with regard to treatment and clinical outcome was performed. Our series consisted of four men and nine women with a mean age of 47 years. Two were diagnosed before operation with ultrasonography-guided core needle biopsy. All patients underwent primary surgical treatment, and four of them were resected by video-assisted thoracic surgery. Seven tumors were malignant and the other six were benign. Immunohistochemical staining showed nestin was positive in three malignant solitary fibrous tumors of pleura (3/7), which were negative for CD34. Except for one, all patients were followed-up for 3 to 35 (mean, 14.5) months. Among them, one patient experienced a recurrence and one patient died of brain metastasis. Ultrasonography-guided core needle biopsy combined with immunohistochemical analysis might be a safe and rapid method to provide a confirmatory diagnosis before resection. For smaller, pedunculated tumors, video-assisted thoracic surgery could be a powerful and useful approach. We speculate that CD34-negative and nestin-positive might be a malignant marker for solitary fibrous tumor of pleura.
ACCESSION #
33372888

 

Related Articles

  • Plevranin Soliter Fibr�z T�m�r� - Olgu Sunumu. Altin, Sedat; �etinkaya, Erdogan; S�k�c�, Sinem Nedime; Karasulu, Levent; Fener, Neslihan // Turk Toraks Dergisi / Turkish Thoracic Journal;Dec2008, Vol. 9 Issue 4, p190 

    Plevranin soliter fibr�z t�m�rleri nadir g�r�len, �ogunlugu benign olan t�m�rlerdir. Tanisi ve tedavisi kitlenin cerrahi rezeksiyonu ile yapilir. Klinik prezentasyonlari kitlenin b�y�kl�g�ne ve intratorasik lokalizasyonuna g�re...

  • Giant Solitary Fibrous Tumor of the Parotid Gland. Chis, Octavian; Albu, Silviu // Case Reports in Medicine;2014, p1 

    Solitary fibrous tumors (SFTs) are rare tumors that are mostly found arising from the pleura. SFT of the parotid gland is a rare tumor; only a few cases have been described in the literature. SFTs are benign in most cases. Clinically, SFTs usually manifest as well circumscribed, slow-growing,...

  • The Role of Cytokeratin 5/6 as an Adjunct Diagnostic Tool in Breast Core Needle Biopsies. Nofech-Mozes, Sharon; Holloway, Claire; Hanna, Wedad // International Journal of Surgical Pathology;Oct2008, Vol. 16 Issue 4, p399 

    In this article, the probability of finding malignancy on surgical excision after applying well-defined morphological criteria combined with immunohistochemical evaluation of cytokeratin 5/6 for the diagnosis of atypical ductal hyperplasia on core biopsies is examined. On the basis of morphology...

  • Intraosseous schwannoma of rib. J Yang // Journal of Clinical Pathology;Feb2009, Vol. 62 Issue 2, p185 

    A case of intraosseous schwannoma of rib is presented. A 22-year-old woman was admitted with paroxysmal thoracic pain, unproductive cough and a hard mass of the thorax. CT scan showed a unilocular osteolystic lesion in the rib. A needle biopsy was performed, and a diagnosis of intraosseous...

  • Surgical oncology and pathology for the private practitioner. Cronin, Kim L. // DVM: The Newsmagazine of Veterinary Medicine;Mar2007, Vol. 38 Issue 3, p4S 

    The article discusses various issues that need to be addressed for each patient to optimize the results of surgery. A pre-surgical diagnosis via aspirate or an incisional biopsy in most cases prior to definitive excision is highly recommended. The ability to accurately determine the extent of...

  • CO2 pneumoperitoneum increases systemic but not local tumor spread after intraperitoneal murine neuroblastoma spillage in mice. Metzelder, Martin; Kuebler, Joachim; Shimotakahara, Akihiro; Vieten, Gertrud; von Wasielewski, Reinhard; Ure, Benno Manfred // Surgical Endoscopy;Dec2008, Vol. 22 Issue 12, p2648 

    Minimally invasive techniques are increasingly used for biopsy and resection of neuroblastoma, but the impact on the behavior of spilled tumor cells is unknown. We aimed to investigate whether CO2 pneumoperitoneum can affect local or systemic tumor manifestation after spillage of neuroblastoma...

  • Factors associated with complete local excision of small rectal carcinoid tumor. Son, Hae-Jung; Sohn, Dae; Hong, Chang; Han, Kyung; Kim, Byung; Park, Ji; Choi, Hyo; Chang, Hee; Oh, Jae // International Journal of Colorectal Disease;Jan2013, Vol. 28 Issue 1, p57 

    Purpose: Although small rectal carcinoid tumors can be treated using local excision, complete resection can be difficult because tumors are located in the submucosal layer. We evaluate the factors associated with pathologically complete local resection of rectal carcinoid tumors. Methods: Data...

  • Pilomatrix carcinoma of scalp. Ersoy, Atilla; Serel, Savaş; Şen, Zeynep; Gültan, Serdar; Heper, Aylin Okçu; Kaya, Burak // European Journal of Plastic Surgery;Jan2006, Vol. 28 Issue 6, p418 

    Pilomatrixoma was first described in 1880. Since then, approximately 73 carcinomas have been reported in the literature. A 57 year-old man was evaluated for a solitary nodule on the left temporoparietal scalp. Biopsy revealed pilomatrixoma. The lesion was treated by wide surgical resection. The...

  • A Glomus Tumour Arising from the Flexor Aspect of the Forearm: A Case Report with Review of the Literature. SINGH NIGAM, JITENDRA; MISRA, VATSALA; SINGH, ANSHUL; KARUNA, VEER; CHAUHAN, SMITA // Journal of Clinical & Diagnostic Research;Nov2012, Vol. 6 Issue 9, p1559 

    A 45 year old male patient presented with the complaint of a purplish nodular painful swelling on the flexor aspect of the left forearm of five years duration. A radiological examination of the lesion was not done prior to its excision. A biopsy was done and it was sent for a histopathological...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics