Anthracofibrosis attributed to mixed mineral dust exposure: report of three cases

Naccache, J.-M.; Monnet, I.; Nunes, H.; Billon-Galland, M.-A.; Pairon, J.-C.; Guillon, F.; Valeyre, D.
July 2008
Thorax;Jul2008, Vol. 63 Issue 7, p655
Academic Journal
Anthracofibrosis, defined as bronchial luminal narrowing with black pigmentation of the overlying mucosa, has been attributed to tuberculosis. Three patients with anthracofibrosis without mycobacterial infection are described who had previous occupational exposure to mixed dusts. CT scans showed calcified hilar lymph nodes in two patients. Surgical biopsy in one patient and autopsy in another revealed fibrotic lymph nodes with black pigmentation. Mineralogical analysis by transmission electron microscopy of pulmonary, hilar and/or bronchial samples found high levels of particle retention, raised percentages of free crystalline silica and mica in two patients, and free crystalline silica, kaolin and other silicates in the third. No evidence of any other contributory factor was found, suggesting that mixed mineral dust was the most probable cause. These observations suggest that exposure to mixed mineral dust should be added to the aetiology of anthracofibrosis.


Related Articles

  • FREQUENCY OF VARIOUS PRESENTATIONS OF TUBERCULOSIS IN PESHAWAR. Khan, Sheema // Gomal Journal of Medical Sciences;Jan2011, Vol. 9 Issue 1, p131 

    Background: Tuberculosis is classified as pulmonary or extra-pulmonary. This study was conducted to determine the frequency of different presentations of tuberculosis in a tertiary care hospital. Material & Methods: This descriptive study was conducted at T.B centre, Hayatabad Medical Complex,...

  • Tuberculous epididymitis associated with abdominal lymphadenopathy (2004:1b). De Backer, A. I.; Mortelé, K. J.; De Roeck, J.; Ros, P. R.; De Keulenaer, B. L.; Vansehoubroeck, I. J.; Bomans, P. // European Radiology;Apr2004, Vol. 14 Issue 4, p748 

    Although the predominant form of tuberculosis is pulmonary disease, an increasing number of cases with extra-pulmonary involvement have been reported. The diagnosis of extra-pulmonary tuberculosis is often difficult because of its protean clinical manifestations and non-specific laboratory...

  • RADIOLOGICAL CASE OF THE MONTH. Gonlugur, Ugur; Kaptanoglu, Melih; Gonlugur, Tanseli // Applied Radiology;Apr2007, Vol. 36 Issue 4, p38 

    The article presents a case of bilateral spontaneous pneumothorax in a patient with miliary pattern tuberculosis. The patient had a history of breathlessness, cough, night sweats, weakness, anorexia, weight loss and fever of 2 days' duration. She had bacillus Calmette-Guérin scars on her left...


    Objective: Prospectively analysing the incidence of tuberculosis in maintenance haemodialysis patients in endemic area for tuberculosis. Materials and Methods: Two year, prospective study in patients on maintenance haemodialysis in three different centres of same region, irrespective of the...

  • Peripancreatic tuberculosis mimicking pancreatic neoplasia Weiss, Eric S.; Klein, Walter M.; Yeo, Charles J. // Journal of Gastrointestinal Surgery;Feb2005, Vol. 9 Issue 2, p254 

    Tuberculosis of the pancreas and peripancreatic lymph nodes is an extremely rare disorder that has been reported with increased frequency in the past several years. Despite the fact that abdominal tuberculosis can generally be managed by pharmacotherapy alone, invasive procedures are often used...

  • Multiple pulmonary nodules: diagnosis in an young afebrile patient. Sodhi, K.S.; Kang, M.; Gulati, M.; Suri, S. // Postgraduate Medical Journal;Jan2003, Vol. 79 Issue 927, p62 

    Presents the case of multiple pulmonary nodules diagnosis in an afebrile patient. Medical history of the patient; Question on the diagnosis of the patient's disease; Causes of the condition.

  • Primary tuberculosis of the oral cavity. R., Kamala; Sinha, Abhishek; Srivastava, Amitabh; Srivastava, Sunita // Indian Journal of Dental Research;Nov/Dec2011, Vol. 22 Issue 6, p835 

    There is a well-known phrase that states, "The more things change, the more they stay the same." This expression continues to apply to tuberculosis (TB), a widespread infectious disease traced back to the earliest of centuries. TB has claimed its victims throughout much of known human history....

  • Epidemiology of Tuberculosis in Northeast of Iran: A Population-Based Study. Rafiee, Soheil; Besharat, Sima; Jabbari, Ali; Golalipour, Faranak; Nasermoaadeli, Ali // Iranian Journal of Medical Sciences;Sep2009, Vol. 34 Issue 3, p193 

    Background: Tuberculosis (TB) is currently one of the greatest problems in public health. Mycobacterium tuberculosis infects about one third of the world's population, of whom more than 80% are living in developing countries. The incidence and prevalence of TB are very different in various parts...

  • Characterization and Management of Paradoxical Upgrading Reactions in HIV-Uninfected Patients with Lymph Node Tuberculosis. Hawkey, Charlotte R.; Yap, Timothy; Pereira, Janis; Moore, David A. J.; Davidson, Robert N.; Pasvol, Geoffrey; Kon, Onn Min; Wall, Robert A.; Wilkinson, Robert J. // Clinical Infectious Diseases;5/1/2005, Vol. 40 Issue 9, p1368 

    In a retrospective analysis, paradoxical deterioration of lymph node tuberculosis in human immuno deficiency virus- uninfected patients was common, occurring in 25 (23%) of 109 patients after treatment had been given for a median of 46 days (interquartile range, 2 1-139 days) and persisting for...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics