TITLE

Why Psychiatric Drugs "Work": The Attribution of Positive Effects Due to Psychological Factors

AUTHOR(S)
Danco, Jeffrey C.
PUB. DATE
March 2008
SOURCE
Ethical Human Psychology & Psychiatry;2008, Vol. 10 Issue 1, p10
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
While outcome research has attempted to elucidate the real benefit of any treatment through randomized, double-blind studies, the role of placebo and other psychological reactions has been given scant but growing attention. This article examines the nature and power of the placebo in the context of antidepressant therapy. Other factors influencing patient reports of positive response are considered, including emotional blunting, victimization, and rebound. It is concluded that the attribution of healing properties to antidepressant drugs is complex and multifaceted, and that the modest advantage of these drugs over placebo may well derive from psychological, not physiological, factors.
ACCESSION #
33294566

 

Related Articles

  • PLACEBO PANACEA. Greenberg, Gary // Mother Jones;Jan/Feb2005, Vol. 30 Issue 1, p20 

    Presents information on Placebo, a sugar pill antidepressant that is being planned to be sold by "Adbusters," a Vancouver, British Columbia-based periodical. Comparison between Placebo and other antidepressants.

  • Serotonergic and Noradrenergic Modulation of Emotion Processing by Single Dose Antidepressants. Brühl, Annette Beatrix; Kaffenberger, Tina; Herwig, Uwe // Neuropsychopharmacology;Jan2010, Vol. 35 Issue 2, p521 

    Serotonergic and noradrenergic pathways are the main targets of antidepressants. Their differential effects on emotion processing-related brain activation are, however, to be further characterized. We aimed at elucidating the neural sites of action of an acute differential serotonergic and...

  • A Benefit-Risk Assessment of Agomelatine in the Treatment of Major Depression. Howland, Robert H. // Drug Safety;2011, Vol. 34 Issue 9, p709 

    The article focuses on a review of the risks and benefits of agomelatine as cure for major depression. It states that agomelatine's efficacy as antidepressant was evaluated in 10 short-term, placebo-controlled studies and three longer-term, relapse prevention, placebo-controlled studies. Results...

  • Are Selective Serotonin Reuptake Inhibitors a Risk Factor for Adolescent Suicide? Healy, David // Canadian Journal of Psychiatry;Feb2009, Vol. 54 Issue 2, p69 

    The article presents a debate concerning the association of Selective Serotonin Re-uptake Inhibitors in adolescent suicide. It notes that the argument from the national suicide rates excludes data from the 1960s and 1970s when the national suicide rates climbed, even the time prescriptions of...

  • Researchers say benefits of antidepressants among pediatric patients outweigh risk of suicide.  // Formulary;Sep2007, Vol. 42 Issue 9, p561 

    The article reports on the result of a study which suggests that the benefits of antidepressants among pediatric patients outweigh the risk of suicide in the U.S. Treatment with antidepressants was associated with an increased risk of suicidal ideation when measured across all trials and...

  • Efficacy and safety of antidepressants for treatment of depression in Alzheimer's disease: a metaanalysis. Thompson, Sarah; Herrmann, Nathan; Rapoport, Mark J.; Lanctôt, Krista L.; Lanctôt, Krista L // Canadian Journal of Psychiatry;Apr2007, Vol. 52 Issue 4, p248 

    Objective: Depression in patients with Alzheimer's disease (AD) is common (15% to 63%) and is associated with significant morbidity and increased mortality. Our objective was to quantitatively summarize the data on the efficacy and safety of antidepressant treatment for depression...

  • Response of depressive symptoms to nortriptyline, phenelzine and placebo. Georgotas, Anastasios; McCue, Robert E.; Friedman, Eitan; Cooper, Thomas B.; Georgotas, A; McCue, R E; Friedman, E; Cooper, T B // British Journal of Psychiatry;Jul87, Vol. 151, p102 

    The effects of nortriptyline, phenelzine, and placebo on 13 symptoms of depression were compared in 75 patients, aged 55 or over, who were suffering from major depression. Nortriptyline and phenelzine were more effective than placebo in treating depression mood, guilt feelings, suicidal...

  • Review: in people with bipolar disorder, short term antidepressants improve clinical response, although tricyclics risk inducing mania. Masand, Prakash; Mago, Rajnish // Evidence Based Mental Health;May2005, Vol. 8 Issue 2, p35 

    The article presents information on the clinical response of antidepressants in people with bipolar disorder. In people with bipolar disorder, antidepressants increase clinical response and remission compared with placebo and do not increase the risk of switching to mania. Tricyclic...

  • Continuing fluoxetine treatment may delay relapse in children and adolescents with major depressive disorder. Wilkinson, Paul // Evidence Based Mental Health;May2005, Vol. 8 Issue 2, p37 

    The article presents information on the effect of continuing fluoxetine treatment in children with major depressive disorder. In children and adolescents who achieve remission from major depression with fluoxetine, continuing fluoxetene treatment can delay relapse compared with switching to...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics