TITLE

Encefalitis chagásica: una complicación tardía postrasplante cardiaco

AUTHOR(S)
De Castro Assis, Alfredo Fernández; Berdugo Sánchez, Alejandra; Cortés, Norma Lucía
PUB. DATE
January 2008
SOURCE
Universitas Médica;ene-mar2008, Vol. 49 Issue 1, p112
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Chagas' disease, also called American trypanosomiasis, is a human tropical parasitic disease that occurs in the Americas, particularly in South America. Its pathogenic agent is a flagellate protozoan named Trypanosoma cruzi, which very rarely involves the central nervous system. Few cases have been reported worldwide literature regarding involvement of the nervous system in Chagas' disease. The majority were associated with immunosuppressive syndromes, especially in patients with acquired immunodeficiency syndrome (AIDS). It has been described in few patients that underwent organ transplantation from an infected donor. Clinical manifestations of Chagas' disease in patients with nervous system involvement may simulate any intracranial lesion with mass effect (e.g., lymphomas) or infections such us diffuse bacterial and viral meningoencephalitis, and opportunistic infection like toxoplasmosis. We describe a case report of a patient with history of cardiac transplant for Chagas' cardiomyopathy who presented with atypical encephalitis 14 months after the procedure, and in whom the imaging findings by CT and MRI scans were very suspicious of nervous system involvement by T. cruzi.
ACCESSION #
33265578

 

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