BMI1 expression associated with survival, GVH disease

Miller, Jeffrey; Harris, Jason; Shafer, Emily
July 2008
Hem/Onc Today;7/25/2008, Vol. 9 Issue 13, p27
The article discusses research being done on the link between BMI1 expression and survival rate in patients who experienced graft-versus-host disease. It references a study published in the 2008 issue of "Blood." The study included 84 patients diagnosed with chronic-phase chronic myelogenous leukemia (CML) and underwent an allogeneic transplant between 1981 and 2002. Researchers found that CML patients who received allogeneic stem cell from an HLA-identical sibling have better overall survival if they have high BMI1 expression.


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