TITLE

Simultaneous UV Spectrophotometric Estimation of Ambroxol Hydrochloride and Levocetirizine Dihydrochloride

AUTHOR(S)
Prabu, S. Lakshmana; Shirwaikar, A. A.; Shirwaikar, Annie; Kumar, C. Dinesh; Kumar, G. Aravind
PUB. DATE
March 2008
SOURCE
Indian Journal of Pharmaceutical Sciences;2008, Vol. 70 Issue 2, p236
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
A novel, simple, sensitive and rapid spectrophotometric method has been developed for simultaneous estimation of ambroxol hydrochloride and levocetirizine dihydrochloride. The method involved solving simultaneous equations based on measurement of absorbance at two wavelengths 242 nm and 231 nm, the λ max of ambroxol hydrochloride and levocetirizine dihydrochloride, respectively. Beer's law was obeyed in the concentration range 10-50 µg/ml and 8-24 µg/ml for ambroxol hydrochloride and levocetirizine dihydrochloride respectively. Results of the method were validated statistically and by recovery studies.
ACCESSION #
32920455

 

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