Fiber-packed SPE tips based on electrospun fibers

Yiyun Zhang; Xuejun Kang; Liqin Chen; Chao Pan; Yingfang Yao; Zhong-Ze Gu
July 2008
Analytical & Bioanalytical Chemistry;Jul2008, Vol. 391 Issue 6, p2189
Academic Journal
A novel fiber-packed solid-phase extraction (SPE) tip was designed based on electrospun nanofibers. The tip was used to investigate the extraction of hydrocortisone (HC), cortisone acetate (CA), ethinylestradiol (EE), and estradiol (E2). The effects of diameters, porous figurations, and functional groups of the electrospun fibers on the selectivity and efficiency were studied. The experimental results indicated that the detection limit of cortisol in water sample could be as low as 0.75 ng/mL. When the tip is used for detection of cortisol in human hair the efficiency of biological sample pretreatment is better than the traditional SPE method. Our method could significantly simplify the traditional SPE process and lower the cost. Industrial application of the tip is anticipated. [Figure not available: see fulltext.]


Related Articles

  • Determination of Aroclor 1248 in Rat Plasma and Liver Matrices: Recovery and Quantification Considerations. Loconto, Paul R. // LC-GC North America;Jun2003 Supplement, Vol. 21 Issue 6, p78 

    Shows the isolation and recovery of Aroclor 1248 from rat plasma and rat liver using probe sonication coupled with reversed-phase solid-phase extraction. Introduction of the chemical to the animal through its peritoneum; Uncertainty in the quantification of four rat liver samples.

  • Automated One Step Solid Phase Extraction (SPE) and Concentration of Organochlorine Pesticides in Water.  // LC-GC North America;Feb2011 Supplement, Vol. 29, p27 

    The article presents a study on the concentration of organochlorine pesticides in water and the use of Automated One Step Solid Phase Extraction (SPE) in the U.S. in 2011. It reveals the use of Automated One Step SPE in Vial Concentration which allows for the most rapid and reproducible...

  • Headspace Liquid Microextraction. Majors, Ronald E.; Wood, Derrick C.; Miller, James M.; Christ, Ingo // LC-GC Asia Pacific;Nov2004, Vol. 7 Issue 4, p8 

    Discusses the similarity between the solid-phase microextraction technique and single-drop microextraction (SDME) method for headspace sampling for gas chromatographic analysis. Classes of residual solvents monitored in pharmaceutical formulations; Headspace SDME results using...

  • Simple and Fast SPE-UPLC-MS-MS Method for an Allergy Tablet Mixture of Acids and Bases. Chambers, Erin; Diehl, Diane; Mazzeo, Jeff // LC-GC Europe;Dec2005 Supplement, Vol. 18, p12 

    The article describes a novel approach to selecting solid-phase extraction methodology based on two protocols and four mixed-mode Oasis sorbents. The components of the tablets used in the study are ibuprofen, pseudoephedrine and chlorpheniramine. The method achieved excellent recoveries for both...

  • Use of solid-phase extraction to enable enhanced detection of acyl homoserine lactones (AHLs) in environmental samples. Schupp, Peter J.; Charlton, Timothy S.; Taylor, Michael W.; Kjelleberg, Staffan; Steinberg, Peter D. // Analytical & Bioanalytical Chemistry;Sep2005, Vol. 383 Issue 1, p132 

    A challenge for understanding the role of bacterial cell–cell signalling in the environment is the detection of those signals, which are often present in low (nmol L−1) concentrations. We describe here a simple purification method, solid-phase extraction (SPE), for increasing the...

  • Advanced Topics in Solid-Phase Extraction: Chemistries. Majors, Ronald E. // LC-GC North America;Jan2007, Vol. 25 Issue 1, p16 

    The article discusses several advances in solid-phase extraction (SPE). SPE has branched out into other areas by employing new formats, new chemistries via novel sorption and partition mechanisms, multidimensional techniques, and miniaturized systems. The approaches used for automation include...

  • Novel In-Tube Solid Phase Microextraction of Aquatic Samples for GC-MS Analysis. Wohleb, R.H.; Okiro, M. // LC-GC North America;Sep2003 Supplement, Vol. 21 Issue 9, p38 

    Presents three novel in tube solid phase microextraction techniques of aquatic samples for gas chromatography - mass spectrometry analysis. Aim of the exercise to reduce sample size and enhance storage integrity; Use of sample agitation with sorptive components for extraction and injection into...

  • Studies on the Chemical Constituents of Cucumber. Hao-xi, BEN; LU Da-dong; BIAN Ning-sheng; WU Mei-fang // Natural Product Research & Development;Jun2008, Vol. 20 Issue 3, p388 

    The volatile components in cucumbers were studied by vacuum distill-freeze concentration, microwave-ultrasonic extraction and solid-phase microextraction (SPME) techniques combined with gas chromatography-mass spectrometry (GC-MS) analyses. 109 compounds have been found in cucumbers' peel, seeds...

  • Solid-phase microextraction of benzimidazole fungicides in environmental liquid samples and HPLC—fluorescence determination. Monzón, A. López; Moreno, D. Vega; Padrón, M. E. Torres; Ferrera, Z. Sosa; Rodríguez, J. J. Santana // Analytical & Bioanalytical Chemistry;Mar2007, Vol. 387 Issue 6, p1957 

    Solid-phase microextraction (SPME) coupled with high-performance liquid chromatography (HPLC) with fluorescence detection was optimized for extraction and determination of four benzimidazole fungicides (benomyl, carbendazim, thiabendazole, and fuberidazole) in water. We studied extraction and...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics