Research
Tags: EMBRYONIC stem cell research; CELL differentiation; EMBRYONIC stem cells -- Therapeutic use; MICROSPHERES (Pharmacy); THERAPEUTICS -- Research; MEDICINE -- Research
Related Articles
- What happened to the stem cells? Hviid Nielsen, T. // Journal of Medical Ethics;Dec2008, Vol. 34 Issue 12, p852
Five partly successive and partly overlapping framings have dominated the public debate about human embryonic stem cells since they first were "derived" a decade ago. Geron Corporation staged the initial framings as 1) basic research and 2) medical hope, but these two were immediately refuted...
- Notch signaling respecifies the hemangioblast to a cardiac fate. Chen, Vincent C; Stull, Robert; Joo, Daniel; Cheng, Xin; Keller, Gordon // Nature Biotechnology;Oct2008, Vol. 26 Issue 10, p1169
To efficiently generate cardiomyocytes from embryonic stem (ES) cells in culture it is essential to identify key regulators of the cardiac lineage and to develop methods to control them. Using a tet-inducible mouse ES cell line to enforce expression of a constitutively activated form of the...
- The Stem Cell Debate. Donohue, John W. // America;11/13/2006, Vol. 195 Issue 15, p25
The article outlines the stem cell debate, which the President George W. Bush along with the senators and the US Conference of Catholic Bishops have opposed it. The senators highlighted the importance of ammending the bill. The article laments at the division between these two groups who are...
- Stem cells with brainpower. Studer, Lorenz // Nature Biotechnology;Dec2001, Vol. 19 Issue 12, p1117
Reports on two studies that provide insight into how human embryonic stem (ES) cell potential can be harnessed toward the generation of brain cells. Diseases that may be treatable with human ES cell research; Induction of neural differentiation by overgrowth of undifferentiated ES cells;...
- Small Molecule Screening with Laser Cytometry Can Be Used to Identify Pro-Survival Molecules in Human Embryonic Stem Cells. Sherman, Sean P.; Pyle, April D. // PLoS ONE;Jan2013, Vol. 8 Issue 1, Special section p1
Differentiated cells from human embryonic stem cells (hESCs) provide an unlimited source of cells for use in regenerative medicine. The recent derivation of human induced pluripotent cells (hiPSCs) provides a potential supply of pluripotent cells that avoid immune rejection and could provide...
- Showing some spine. Schultz, Stacey // U.S. News & World Report;12/13/99, Vol. 127 Issue 23, p67
Focuses on human embryonic stem cell research and the treatment of paralysis. Study from Washington University School of Medicine, published in a December 1999 issue of `Nature Medicine' that could lead to a cure for spinal cord injuries; How transplanted undifferentiated cells helped to repair...
- Electrophysiological Properties of Embryonic Stem Cell- Derived Neurons. Risner-Janiczek, Jessica R.; Ungless, Mark A.; Li, Meng // PLoS ONE;2011, Vol. 6 Issue 8, p1
In vitro generation of functional neurons from embryonic stem (ES) cells and induced pluripotent stem cells offers exciting opportunities for dissecting gene function, disease modelling, and therapeutic drug screening. To realize the potential of stem cells in these biomedical applications, a...
- Intrinsic transition of embryonic stem-cell differentiation into neural progenitors. Kamiya, Daisuke; Banno, Satoe; Sasai, Noriaki; Ohgushi, Masatoshi; Inomata, Hidehiko; Watanabe, Kiichi; Kawada, Masako; Yakura, Rieko; Kiyonari, Hiroshi; Nakao, Kazuki; Jakt, Lars Martin; Nishikawa, Shin-ichi; Sasai, Yoshiki // Nature;2/24/2011, Vol. 470 Issue 7335, p503
The neural fate is generally considered to be the intrinsic direction of embryonic stem (ES) cell differentiation. However, little is known about the intracellular mechanism that leads undifferentiated cells to adopt the neural fate in the absence of extrinsic inductive signals. Here we show...
- Effect of substrate stiffness on early human embryonic stem cell differentiation. Eroshenko, Nikolai; Ramachandran, Rukmani; Yadavalli, Vamsi K.; Rao, Raj R. // Journal of Biological Engineering;2013, Vol. 7 Issue 1, Special section p1
Background: The pluripotency and self renewing properties of human embryonic stem cells (hESC) make them a valuable tool in the fields of developmental biology, pharmacology and regenerative medicine. Therefore, there exists immense interest in devising strategies for hESC propagation and...
