TITLE

Effect of erythromycin on image quality and transit time of capsule endoscopy: A two-center study

AUTHOR(S)
Niv, Eva; Bogner, Ido; Barkay, Olga; Halpern, Zamir; Mahajna, Elisabeth; Depsames, Roman; Kopelman, Yael; Fireman, Zvi; Herrlinger, Klaus R.
PUB. DATE
April 2008
SOURCE
World Journal of Gastroenterology;4/28/2008, Vol. 14 Issue 16, p2561
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
AIM: To compare the effect of oral erythromycin vs no preparation with prokinetics on the transit time and the image quality of capsule endoscopy (CE) in evaluating small bowel (SB) pathology. METHODS: We conducted a retrospective, blinded (to the type of preparation) review of 100 CE studies, 50 with no preparation with prokinetics from one medical center (Group A) and 50 from another center with administration of a single dose of 200 mg oral erythromycin 1 h prior to CE (Group B). Gastric, SB and total transit times were calculated, the presence of bile in the duodenum was scored, as was cleanliness within the proximal, middle and distal intestine. RESULTS: The erythromycin group had a slightly shorter gastric transit time (21 min vs 28 min, with no statistical significance). SB transit time was similar for both groups (all P > 0.05). Total transit time was almost identical in both groups. The rate of incomplete examination was 16% for Group A and 10% for Group B (P = 0.37). Bile and cleanliness scores in different parts of the intestine were similar for the two groups (P > 0.05). CONCLUSION: Preparation for capsule endoscopy with erythromycin does not affect SB or total transit time. It tends to reduce gastric transit time, but it does not increase the cecum-reaching rate. Erythromycin does not adversely affect image quality. We consider the routine use of oral erythromycin preparation as being unjustified, although it might be considered in patients with known prolonged gastric emptying time.
ACCESSION #
32582925

 

Related Articles

  • Small Bowel Tumors and Videocapsule: a Productive Union. Urbain, Daniel // Journal of Gastrointestinal & Liver Diseases;Mar2010, Vol. 19 Issue 1, p9 

    The article discusses the capsule endoscopy, an effective tool for small bowel disease examination which provides subsequent patient management in medical cases. The author emphasized that the treatment showed cost effectiveness and quality of patient's management based on radiological...

  • A diagnosis support system for capsule endoscopy. Yagi, Y.; Vu, H.; Echigo, T.; Sagawa, R.; Yagi, K.; Shiba, M.; Higuchi, K.; Arakawa, T. // Inflammopharmacology;Apr2007, Vol. 15 Issue 2, p78 

    The diagnostic time required for a full, 8-hour video capsule endoscopy is usually between 45 and 120 min. The aim of this work is to evaluate the diagnostic time required when applying a method that adaptively controlls the image display rate. The advantage of the method is that the sequence...

  • Capsule Endoscopy-Where Are We at 2011 and Where Are We Headed? Eliakim, Rami // Intestinal Research;2012, Vol. 10 Issue 3, p235 

    Since its introduction over 10 years ago, capsule endoscopy has become an important investigational tool of small bowel, and thereafter of esophageal and colonic pathologies. Over the years, 2nd generation capsules were developed for all three sites, as was a non-video 2nd generation agile...

  • 'Intelligent' pills, active capsules to offer significant competition. Brosky, John // Diagnostics & Imaging Week;11/15/2007, Vol. 10 Issue 46, p1 

    The article reports on the introduction of ingestible camera capsules during the United European Gastroenterology Week in Paris, France in November 2007. The presentation of these camera capsules highlighted features on lighting and wireless transmission. According to the Millennium Research...

  • Bleeding Jejunal Dieulafoy Pseudopolyp: Capsule Endoscopic Detection and Laparoscopic-Assisted Resection. Prasad, T. R. Sai; Kwang Hsien Lim; Kiat Hon Lim; Te-Lu Yap // Journal of Laparoendoscopic & Advanced Surgical Techniques;Aug2007, Vol. 17 Issue 4, p509 

    In this paper, we report a case of bleeding solitary jejunal Dieulafoy pseudopolyp that was detected on capsule endoscopy and treated with a laparoscopic-assisted transumbilical polypectomy procedure. This case illustrates an innovative, tailored application of minimal invasive techniques in the...

  • Incidence of tumoral pathology according to study using capsule endoscopy for patients with obscure gastrointestinal bleeding. Estévez, E.; González-Conde, B.; Vázquez-Iglesias, J. L.; Alonso, P. A.; De los Angeles Vázquez-Millán, M.; Pardeiro, R. // Surgical Endoscopy;Oct2007, Vol. 21 Issue 10, p1776 

    Capsule endoscopy has involved a significant advance in techniques for imaging of the small bowel. Its most frequent indication is for studying patients with obscure gastrointestinal bleeding (OGIB). Small bowel tumors are infrequent, representing only 1% to 3% of all malignant gastrointestinal...

  • How Should We Train Capsule Endoscopy? A Pilot Study of Performance Changes During a Structured Capsule Endoscopy Training Program. Postgate, Aymer; Haycock, Adam; Fitzpatrick, Aine; Schofield, Gill; Bassett, Paul; Thomas-Gibson, Siwan; Fraser, Chris // Digestive Diseases & Sciences;Aug2009, Vol. 54 Issue 8, p1672 

    There are no validated training/accreditation guidelines for capsule endoscopy. We assessed the utility of a structured training program on two experienced gastroenterologists and one endoscopy nurse. Validated studies were standardized for difficulty in blocks of three. Trainees completed a...

  • Prospective evaluation of small bowel preparation with bisacodyl and sodium phosphate for capsule endoscopy. Franke, Andreas; Hummel, Frank; Knebel, Phillip; Antoni, Christoph; Böcker, Ulrich; Singer, Manfred V.; Löhr, Matthias; Mulder, Chris J. J. // World Journal of Gastroenterology;4/7/2008, Vol. 14 Issue 13, p2061 

    AIM: To determine the effect of Prepacol®, a com-bination of sodium phosphate and bisacodyl, on transit and quality of capsule endoscopy (CE). METHODS: Fivety two consecutive patients were included in this prospective study. CE was performed following a 12 h fasting period. Twenty six...

  • Effectiveness of polaprezinc for low-dose aspirin-induced small-bowel mucosal injuries as evaluated by capsule endoscopy: a pilot randomized controlled study. Watari, Ikue; Oka, Shiro; Tanaka, Shinji; Aoyama, Taiki; Imagawa, Hiroki; Shishido, Takayoshi; Yoshida, Shigeto; Chayama, Kazuaki // BMC Gastroenterology;2013, Vol. 13 Issue 1, p1 

    Background: Treatment of low-dose aspirin (LDA)-induced small-bowel injury has not been established. Polaprezinc, a chelate of zinc and L-carnosine, may be efficacious for such injury. We conducted a pilot randomized controlled study to investigate whether polaprezinc is effective...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics