TITLE

Association between plasma lipid levels and migraine in subjects aged =50 years: preliminary data from the Zab�t Aging Project

AUTHOR(S)

Monastero, Roberto; Pipia, Carmela; Cefal�, Angelo B.; Liveri, Eva Turco; Rosano, Rosamaria; Camarda, Rosolino; Camarda, Cecilia

PUB. DATE

May 2008

SOURCE

Neurological Sciences;May2008 Supplement 1, Vol. 29, p179

SOURCE TYPE

Academic Journal

DOC. TYPE

Article

ABSTRACT

We evaluated the association between lipid levels and migraine using cross-sectional, population-based data of 1809 subjects aged =50 years; 151 subjects with migraine and 1658 nonmigraineurs were included. Diagnosis of migraine was carried out using the criteria of the International Headache Society. The following plasma lipids were collected: total cholesterol (TC), lowdensity lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG). Only TC ( p<0.003) and LDL-C levels ( p<0.004) were significantly higher in migraineurs than nonmigraineurs. After multiple adjustments, only elevated TC (=220 mg/dl) was significantly associated with migraine (OR [95% CI]=1.6 [1.1�2.3]); this association increased in elderly males with migraine (OR [95% CI]=3.8 [1.4�9.9]). According to our results, TC plasma levels should be closely monitored in elderly males with migraine.

ACCESSION #

32562626

Tags: MIGRAINE;  STEROLS;  ISOPENTENOIDS;  HEADACHE;  THERAPEUTICS

 

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