Exposure to inhalable dust and its cyclohexane soluble fraction since the 1970s in the rubber manufacturing industry in the European Union

de Vocht, F.; Vermeulen, A.; Burstyn, I.; Sobala, W.; Dost, A.; Taeger, D.; Bergendorf, U.; Strait, K.; Swuste, P.; Kromhout, H.
June 2008
Occupational & Environmental Medicine;Jun2008, Vol. 65 Issue 6, p384
Academic Journal
Objectives: As exposures to airborne particulates in the European rubber industry might still be causing genotoxic risks, it is important to assess trends in levels of inhalable dust and its cyclohexane soluble fraction (CSF) between the 1970s and 2003. Methods: 13 380 inhalable and 816 respirable dust and 5657 CSF measurements, collected within the framework of the European Union Concerted Action EXASRUB, were analysed. Hierarchical mixed effects models were applied to assess exposure trends, taking into account between-factory, between-worker/location and day-to-day variances. Results: Geometric mean levels of inhalable dust and CSF exposure changed by -4% (range -5.8 to +2.9%) and -3% (range -8.6 to 0%( per year, respectively. Significant reductions in inhalable dust concentrations were found in all countries for handling of crude materials and mixing and milling (-7% to -4% per year), as well as for miscellaneous workers (-11% to -5% per year), while significant CSF exposure reductions were found in curing (-8.6% per year) and maintenance and engineering departments (-5.4% per year). Conclusion: These analyses suggest that on average exposure levels of inhalable dust and its CSF in the European rubber manufacturing industry have steadily declined. Most likely genotoxic risks have also lessened over time since exposure levels have decreased and the most toxic chemicals have been replaced. In addition to differences in exposure reductions and levels among various stages of the production process, large differences across countries were noted. These patterns should be taken into account in retrospective assessment of exposure for epidemiological studies assessing cancer risk in the rubber industry.


Related Articles

  • Exposures and reported symptoms associated with occupational deployment to the Buncefield fuel depot fire, England 2005. Morgan, O.; Verlander, N. Q.; Kennedy, F.; Moore, M.; Birch, S.; Kearney, J.; Lewthwaite, P.; Lewis, R.; O'Brian, S.; Osman, J.; Reacher, M. // Occupational & Environmental Medicine;Jun2008, Vol. 65 Issue 6, p404 

    Objectives: An explosion at the Buncefield fuel depot outside London occurred on 11 December 2005. We conducted a retrospective cohort study of airborne exposures and health status for workers deployed. Methods: Deployed individuals were identified through their occupational health departments....

  • An Anthropology of Air. Batchelder, Tim // Townsend Letter for Doctors & Patients;Nov2005, Issue 268, p105 

    Presents an article that talks about the history of one air-borne disease, tuberculosis, and how it reveals the sea change in perceptions of where diseases come from and what can be done about them. Relationship of tuberculosis to the growing number of poor population; Contribution of laboratory...

  • Beat the bugs. Wilks, Neil // Professional Engineering;6/29/2005, Vol. 18 Issue 12, p33 

    The article cites a study on bugs and superbugs like Staphylococcus aureus (MRSA) responsible for spreading infection. One of the regular features of the tabloid press in recent months has been headlines about so-called superbugs such as MRSA. A worldwide team of experts assembled to discuss...

  • A SEASON-DEPENDENT VARIATION OF GENOTOXICITY OF SURFACE WATER SAMPLES FROM TAIHU LAKE, YANGZTE DELTA. Jian-Yong Wu; Lei Shen; Guang Gao; Guo-Fang Lin; Xin Ke; Jian-Hua Shen // Environmental Monitoring & Assessment;Nov2004, Vol. 98 Issue 1-3, p225 

    The present study is to assess a year round change of genotoxicity of surface water in Taihu Lake, Yangtze delta. The water samples were collected in spring, summer, autumn and winter of 2001, respectively. The bacterial L-arabinose resistance forward mutation test (ara test), along with the...

  • Questions.  // Occupational Medicine;1999, Vol. 49 Issue 3, p203 

    No abstract available.

  • Answers.  // Occupational Medicine;1999, Vol. 49 Issue 3, p205 

    No abstract available.

  • Insight: Questions.  // Occupational Medicine;1999, Vol. 49 Issue 4, p271 

    No abstract available.

  • Insight: Answers.  // Occupational Medicine;1999, Vol. 49 Issue 4, p273 

    No abstract available.

  • Medical surveillance. Lewis, Anne // Industrial Safety & Hygiene News;Jul2002, Vol. 36 Issue 7, p38 

    Discusses the process of medical surveillance program for early detection of work-related illness. Information gathering; Needs assessment; Selection of proper population and proper tests; Protocol for using and interpreting test results; Intervention process; Well-known chemical exposures.


Read the Article


Sign out of this library

Other Topics