Foxp3 and microsatellite stability phenotype in colorectal cancer

Laddenkemper, Christoph; Nagorsen, Dirk; Zeitz, Martin
June 2008
Gut;Jun2008, Vol. 57 Issue 6, p725
Academic Journal
The article focuses on Foxp3 and microsatellite stability in colorectal cancer. The discovery of differential Foxp3 expression in microstellite-stable (MSS) tumors compared with high-frequency microsatellite instability (MSI-H) in colorectal cancer (CRC) suggests investigation of the cellular response in CRC. Tumor therapy with immunotherapeutic or vaccine regimens that targets T cells might be the best treatment for CRC patients.


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