TITLE

Učestalost i faktori rizika za razvoj pankreatitisa i asimptomatske hiperamilazemije nakon endoskopske retrogradne holangiopankreatografije - naša iskustva

AUTHOR(S)
Lukić, S.; Alempijević, T.; Jovanović, I.; Popović, D.; Krstić, M.; Uglješić, M.
PUB. DATE
March 2008
SOURCE
Acta Chirurgica Iugoslavica;2008, Vol. 55 Issue 1, p17
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Introduction: Chronic pancreatitis is defined as chronic inflammatory lesion of pancreatic parenchyma leading to destruction and fibrosis of exocrine pancreas. Endoscopic retrograde cholangiopancreatography (ERCP) is the most sensitive and specific method for detection of morphological alterations in chronic pancreatitis. ERCP is inevitably associated to post-ERCP acute pancreatitis, as well as hyperamilasemia. Study aim: This study aims to determine frequency of post - ERPC pancreatitis and asymptomatic hyperamilasemia. Study methods: We have studied 160 patients who underwent ERCP in lnstitute of Digestive Diseases, Clinical Centre of Serbia in Belgrade. Data regarding cholecystectomy, papillotomy, peripapillary diverticulosis, Oddi's sphincter hypertension, choledoch canulation and diameter, Wirsung duct canulation, minor duodenal papilla patency, anomalies of BP junction, as well as chronic pancreatitis has been analysed and correlated with eventual development of post-ERCP pancreatitis and asymptomatic hyperamilasemia. Results: Asymptomatic hyperami lasemia was determined in 51 subjects (31.9%), while pancreatitis has been developed in 5 patients (3.1%) subsequent to ERCP. It has been proofed that Wirsung duct canulation plays significant role in development of post-ERCP complications. Conclusion: Although numerous factors may potentially contribute to development of post-ERCP pancreatitis, none of them, with the exception of Wirsung duct canulation, has been determined to play significant role in development of these complications.
ACCESSION #
32462490

 

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