Pharmacogenetic-guided and standard dosing did not differ for out-of-range INRs in patients initiating warfarin therapy

Garcia, David
March 2008
ACP Journal Club;Mar/Apr2008, Vol. 148 Issue 2, p19
Academic Journal
The article focuses on the randomized controlled trial (RCT) investigating how pharmacogenetic-guided dosing (PGD) and standard dosing (SD) compare for percentage of out-of-range international normalized ratios (INRs) in patients initiating oral anticoagulation with warfarin. The trial, conducted with 206 patients (18 to 86 years of age) found out that PGD and SD did not differ for out-of-range INRs in patients initiating warfarin therapy.


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