TITLE

Intraarticular hylan was no better than hyaluronic acids for osteoarthritis of the knee

AUTHOR(S)
Hunter, David
PUB. DATE
March 2008
SOURCE
ACP Journal Club;Mar/Apr2008, Vol. 148 Issue 2, p16
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article focuses on the randomized controlled trial (RCT) investigating the relative efficacy and safety of intraarticular hylan and 2 hyaluronic acids (HAs) for osteoarthritis (OA) of the knee. The trial conducted with 660 patients (with the mean age of 63 years) found out that intraarticular hylan was not more effective or safe than HAs for OA of the knee.
ACCESSION #
32435139

 

Related Articles

  • Hyaluronic Acid in the Treatment of Knee Osteoarthritis. Colen, Sascha; van den Bekerom, Michel P. J.; Mulier, Michiel; Haverkamp, Daniël // BioDrugs;2012, Vol. 26 Issue 4, p257 

    Background: Although accepted as a conservative treatment option for knee osteoarthritis, the debate about the effectiveness of intra-articular treatment with hyaluronic acid (HA) is still ongoing because of contrasting outcomes in different clinical studies. Several well designed clinical...

  • Hyaluronic Acid for the Treatment of Osteoarthritis in all Joints Except the Knee. Colen, Sascha; Haverkamp, Daniel; Mulier, Michiel; van den Bekerom, Michel P.J. // BioDrugs;2012, Vol. 26 Issue 2, p101 

    Background: The use of intra-articular hyaluronic acid (HA) is a well known treatment in patients with knee osteoarthritis (OA). In other joints, less evidence is available about the efficacy of treatment with intraarticular HA. HA is also used intra-articularly in the metatarsophalangeal-1...

  • Hyaluronan inhibits IL-1β-stimulated collagenase production via down-regulation of phosphorylated p38 in SW-1353 human chondrosarcoma cells. Julovi, Sohel M.; Ito, Hiromu; Hiramitsu, Teruko; Yasuda, Tadashi; Nakamura, Takashi // Modern Rheumatology (Springer Science & Business Media B.V.);Jun2008, Vol. 18 Issue 3, p263 

    We investigated the intracellular mechanism for the inhibitory effects of hyaluronan (HA) on interleukin-1β (IL-1β)-stimulated collagenase-1 and -3 (matrix metalloproteinases (MMPs)-1 and -13) production in a human chondrosarcoma cell line, SW-1353. MMPs-1 and -13 were induced by IL-1β...

  • Bringing arthritis to its knees.  // Alive: Canada's Natural Health & Wellness Magazine;Jan2004, Issue 255, p16 

    Reports on the possible benefits of hyaluronic acid in offering relief for osteoarthritis. Role of hyaluronic acid in tissue hydration and cellular function; Investigation of the value of using hyaluronic acid orally in treating osteoarthritis.

  • Hyaluronic acid injections show pain relief for knee OA, promise in other joint areas. Brockenbrough, Gina // Orthopedics Today;Feb2008, Vol. 28 Issue 2, p61 

    The article provides information on a study which investigated the use of hyaluronic acid (HA) injections to treat osteoarthritis. Physician David R. Diduch presented the findings at the Insall Scott Kelly Institute Sports Medicine and Total Knee & Hip Symposium. According to the article, the...

  • Retrospective study of the effect of intra-articular treatment of osteoarthritis of the distal tarsal joints in 51 horses. Labens, R.; Mello, D.J.; Voûte, L.C. // Veterinary Record: Journal of the British Veterinary Association;11/3/2007, Vol. 161 Issue 18, p611 

    Osteoarthritis of the distal tarsal joints, affecting the centrodistal and tarsometatarsal joints, is a common cause of hindlimb lameness in horses. This paper describes the outcome of the intra-articular treatment of 51 horses with the condition with either methylprednisolone acetate (MPA) or...

  • Osteoartritte Ä°ntraartiküler Hyalüronik Asit Tedavisi. Diraçoğlu, Demirhan // Turkish Journal of Physical Medicine & Rehabilitation / Turkiye ;dec2007, Vol. 53 Issue 4, p154 

    Osteoarthritis (OA) is the most common chronic joint disease in the world. Intra-articular hyaluronic acid (HA) managements have been pervading increasingly in the OA treatment. But many physicians have still plenty of questions about this method. In this article, intra-articular HA management...

  • Non-Animal Stabilised Hyaluronic Acid in the Treatment of Osteoarthritis of the Knee: A Tolerability Study. Åkermark, C.; Berg, P.; Björkman, A.; Malm, P. // Clinical Drug Investigation;2002, Vol. 22 Issue 3, p157 

    Objective: To evaluate the safety of an intra-articular injection of non-animal stabilised hyaluronic acid (NASHA) in patients with osteoarthritis (OA) of the knee. Design and setting: Non-blind prospective study conducted at five centres in Sweden. Patients and participants: 103 patients aged...

  • Treatment of osteoarthitis of the knee by intra-articular hyaluronic acid. Briliantono, M. Soenarwo // Immunology & Cell Biology;Apr1996, Vol. 74 Issue 2, special section pA16 

    This article discusses various issues related to the treatment of osteoarthitis of the knee by intra-articular hyaluronic acid. The objective of this randomized, double-blind, placebo-controlled study was to evaluate the effects of a 1% hyaluronic acid solution, in comparison with physiological...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics