TITLE

Chemotherapy with enteric-coated tegafur/uracil for advanced hepatocellular carcinoma

AUTHOR(S)
Ishikawa, Toru; Ohwada, Susumu
PUB. DATE
May 2008
SOURCE
World Journal of Gastroenterology;5/14/2008, Vol. 14 Issue 18, p2797
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide, including Japan. Although the development of imaging modalities has made the early diagnosis of HCC possible, surgically resectable cases are relatively uncommon because of hepatic function reserve and/or an advanced stage at presentation. Several modalities, such as transcatheter arterial chemoembolization, percutaneous ethanol injection, microwave coagulation therapy and radiofrequency ablation are reportedly useful in treating patients with non-resectable disease. However, unfortunately, many HCC patients have tumor recurrence. The overall prognosis of patients with HCC is very poor, and treatment of the advanced form is still problematic. In this article, we review the clinical efficacy and toxicity of enteric-coated tegafur/uracil in the treatment of patients with advanced non-resectable HCC.
ACCESSION #
32152090

 

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