Is Total Colonic Evaluation for Anal Cancer Necessary?

Wasvary, Harry J.; Barkel, Donald C.; Klein, Steven N.
June 2000
American Surgeon;Jun2000, Vol. 66 Issue 6, p592
Academic Journal
The purpose of this study was to evaluate the necessity of total colonic evaluation in patients diagnosed with anal cancer. We reviewed the cases of 69 patients treated for neoplasm of the anus from January 1973 through November 1998. Patients underwent a barium enema, flexible sigmoidoscopy or colonoscopy; findings from these procedures were analyzed. Anal pathology included: squamous cell carcinoma, 48 patients (72%); adenocarcinoma, 6 patients (9%); and squamous cell carcinoma in situ, 10 patients (15%). Chemoradiation was completed in 41 patients (61%), and 6 patients (9%) underwent abdominal perineal resection. Wide excision was the primary therapy in 15 patients (22%). Procedures included: colonoscopy, 31 patients (46%); flexible sigmoidoscopy only, 15 patients (22%); barium enema only, 3 patients (5%); and a combination of flexible sigmoidoscopy and barium enema, 18 patients (27%). Eighty-five per cent of patients had a normal colonic evaluation. Ten patients (15%) had single or multiple polyps identified. Six adenomatous polyps and two hyperplastic polyps were found. No synchronous colorectal malignancy was identified. We conclude that colonoscopy is an integral part of colonic surveillance in patients diagnosed with anal carcinoma, but our study fails to find evidence to support such intervention. The standard screening recommendation for colorectal cancer based on age and risk factors is appropriate intervention for patients diagnosed with anal cancer; anal cancer itself does not appear to be one of these risk factors.


Related Articles

  • What You Need to Know About Anal cancer.  // Tennessee Tribune;4/19/2012, Vol. 23 Issue 17, p4B 

    The article presents information on the anal cancer and its physical exams including digital rectal examination, anoscopy and proctoscopy.

  • HIV, cancer, and male Pap smears. Cohan, Gary R. // Advocate;2/7/95, Issue 674, p44 

    Reports that men with a history of anal intercourse and anal warts should be regularly screened for anal cancer or precancerous lesions. Study of anal cancer in HIV-positive men; Risk in men with AIDS; Implication of the common wart virus.

  • Smear test developed for anal cancer.  // Gastrointestinal Nursing;Nov2008, Vol. 6 Issue 9, p4 

    The article reports on the development of a smear test for anal cancer by the scientists in Cambridge, Massachusetts. The test is based on the fact that normal anal tissue lacks minichromosome maintenance proteins (MCMs). The MCM testing has the ability to detect anal cancer in 235 anal smears...

  • Molecular markers may improve colon cancer staging, screening. McCann, Jean; McCann, J // JNCI: Journal of the National Cancer Institute;07/05/2000, Vol. 92 Issue 13, p1039 

    Reports on how molecular markers can help in improving the screening and staging of colon cancer. Problem of understaging in colon cancer patients; Statements of Anton Bilchik, assistant director of surgical oncology at John Wayne Cancer Institute in Santa Monica, California, on the possible...

  • Colon cells for cancer screening. Nair, Padmanabhan P. // Agricultural Research;Oct98, Vol. 46 Issue 10, p23 

    Discusses a technique for early diagnosis of colorectal cancer based on the isolation of live colon cells from stool samples. Background information on colon cancer; Details on the diagnostic method; How it was discovered by a scientist at the Agricultural Research Service of the United States...

  • Closely Screen Relatives of Sporadic Colorectal Cancer Patients.  // Modern Medicine;Oct98, Vol. 66 Issue 10, p12 

    Discusses the abstract of the article `Colonoscopic screening in first-degree relatives of patients with `sporadic' colorectal cancer: A case control study,' by A. Pariente, C. Milan et al, published in the July 1998 issue of the `Gastroenterology' periodical.

  • Surveillance after positive and negative colonoscopy examinations: issues, yields, and use Schoen, Robert E. // American Journal of Gastroenterology;Jun2003, Vol. 98 Issue 6, p1237 

    As colorectal cancer screening gains acceptance by the public, the use of colonoscopy will increase. The frequency of surveillance examinations after detection of an adenoma is one of the largest contributors to the cost of colorectal cancer screening. Ten years after the publication of the...

  • Is there a true “shift” to the right colon in the incidence of colorectal cancer? Rabeneck, Linda; Davila, Jessica A.; El-Serag, Hashem B. // American Journal of Gastroenterology;Jun2003, Vol. 98 Issue 6, p1400 

    : ObjectivePrevious studies have reported a migration in the occurrence of colorectal cancer (CRC) toward a proximal colonic location. To assess the potential impact of this, we evaluated recent temporal trends in the United States.: MethodsUsing the nine population-based cancer registries that...

  • Parathyroid hormone-related protein expression in the human colon: Immunohistochemical evaluation. Malakouti, S.; Asadi, F.K. // American Surgeon;Jul1996, Vol. 62 Issue 7, p540 

    Evaluates the expression of parathyroid hormone-related protein (PTHrP) by immunohistochemical staining in tissue samples from normal colorectal mucosa, polyps and colorectal carcinoma removed from the same patients. Use of commercially available monoclonal antibody; Enhancement of PTHrP...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics