Gut, inflammation and osteoporosis: basic and clinical concepts
- Therapie chronisch-entzÃ¼ndlicher Darmerkrankungen. Mecklenburg, Ingo // Praxis (16618157);2/12/2014, Vol. 103 Issue 4, p203
Inflammatory Bowel Disease (i.e. Crohn's Disease and Ulcerative Colitis) show a rising incidence throughout Switzerland. An early and individualized therapy usually enables the effective treatment of both diseases and prevents structural gastrointestinal damage or surgical interventions. The...
- Natalizumab. // Reactions Weekly;6/25/2005, Issue 1057, p14
Discusses research being done on progressive multifocal leukoencephalopathy after natalizumab therapy for Crohn's disease. Reference to a study by G. Van Assche et al published in the 2005 issue of the "New England Journal of Medicine"; Findings of the study.
- Clinical epidemiology -- how important now? Binder, V // Gut;May2005, Vol. 54 Issue 5, p574
The article focuses on the putative risk of haematopoietic cancer in relation to modern strong immunosuppressive treatment in inflammatory bowel disease. The natural history of a chronic disease should ideally be the background for any therapeutic trial. Modern information technology has...
- Effects of Antioxidant Polyphenols on TNF-Alpha-Related Diseases. Kawaguchi, Kiichiro; Matsumoto, Tsukasa; Kumazawa, Yoshio // Current Topics in Medicinal Chemistry;Jul2011, Vol. 11 Issue 14, p1767
Oxidative stress and inflammatory responses sustained for a long period of time cause many diseases. A proinflammatory cytokine, tumor necrosis factor a (TNF-a), plays a pivotal role in the pathogenesis of chronic and autoimmune diseases. The present review, supplemented by hitherto unpublished...
- A Comparison of Methotrexate with Placebo for the Maintenance of Remission in Crohn's Disease. Feagan, Brian G.; Fedorak, Richard N.; Irvine, E. Jan; Wild, Gary; Sutherland, Lloyd; Steinhart, A. Hillary; Greenberg, Gordon R.; Koval, John; Wong, Cindy J.; Hopkins, Marybeth; Hanauer, Stephen B.; McDonald, John W.D. // New England Journal of Medicine;06/01/2000, Vol. 342 Issue 22, p1627
Background: Patients with Crohn's disease often have relapses. Better treatments are needed for the maintenance of remission. Although methotrexate is an effective short-term treatment for Crohn's disease, its role in maintaining remissions is not known. Methods: We conducted a double-blind,...
- Altheus Targets Bowel Diseases With Combination Approach. Young, Donna // BioWorld Today;12/17/2007, Vol. 18 Issue 243, p1
The article deals with the effort of Altheus Therapeutics Inc. to develop a combination approach to treating inflammatory bowel disease (IBD). There are two chronic diseases that cause intestinal inflammation. The incidence of IBD in the U.S. and Europe is cited. According to Chief Executive...
- Manchester University heads Â£10m EU-funded research network into inflammatory bowel disease. // Gastrointestinal Nursing;Apr2013, Vol. 11 Issue 3, p6
The article reports that the University of Manchester is leading a 10 million Sterling Pound, 5-year research network to identify better treatments for inflammatory bowel diseases (IBD), such as Crohn's disease (CD) and ulcerative colitis (UC).
- Le malattie infiammatorie croniche intestinali in etÃ pediatrica. Pelosi, Paola; Cianchi, Ilaria; Paolacci, Giulia; Gissi, Anna; Paci, Monica; Naldini, Sara; Lionetti, Paolo // Children's Nurses: Italian Journal of Pediatric Nursing Science ;inverno2012/2013, Vol. 4 Issue 4, p122
Chronic inflammatory bowel diseases include two important conditions: Crohn disease and Ulcerative Colitis. Although they were considered rare among children in the past, these diseases have seen in the last decades a progressive increase in their incidence also in developing ages, and now they...
- Pyoderma Gangrenosum Associated With Inflammatory Bowel Disease. Report of Two Cases With Good Response to Infliximab. Carrasco Cubero, Carmen; Ruiz Tudela, M. Mar; Salaberri Maestrojuan, José Javier; Pérez Venegas, José Javier // Reumatologia Clinica;mar/abr2012, Vol. 8 Issue 2, p90
Among the extraintestinal manifestations of inflammatory bowel disease (IBD), pyoderma gangrenosum (PG) often poses a therapeutic challenge. We describe two cases of PG associated with inflammatory bowel disease, who responded to treatment with Infliximab.