Does Helicobacter pylori protect against asthma and allergy?

Blaser, Martin J.; Yu Chen; Reibman, Joan
May 2008
Gut;May2008, Vol. 57 Issue 5, p561
Academic Journal
The article examines the protective role of Helicobacter pylori against asthma and allergy. It explores the evidence which relates to increased manifestation of several disorders such as energy homeostasis and asthma in the absence of H. pylori. It also discusses the potential of gastric H. pylori colonisation in protecting people from other diseases as well as the factors causing its growth in the human stomach.


Related Articles

  • H. pylori infection linked to absence of asthma and allergies. Richards, Cassandra A.; Stott, Bob; Volansky, Rob; Wray, Charles // Infectious Diseases in Children;Apr2012, Vol. 25 Issue 4, p20 

    The article reports on the association between Helicobacter pylori infection and the absence of asthma and allergies in children based on a study by C. Camacho et al. presented at the American Academy of Allergy, Asthma & Immunology (AAAAI) 2012 Annual Meeting held in Orlando, Florida.

  • Characterization of Expression of a Functionally Conserved Helicobacter pylori Methyltransferase-Encoding Gene within Inflamed Mucosa and during In Vitro Growth. Takeuchi, Hiroaki; Israel, Dawn A.; Miller, Geraldine G.; Donahue, John P.; Krishna, Uma; Gaus, Kristin; Peek Jr., Richard M. // Journal of Infectious Diseases;10/15/2002, Vol. 186 Issue 8, p1186 

    Methylation of bacterial DNA can regulate microbial growth and virulence. Expression of hpyIM, a conserved methyltransferase of the gastric pathogen Helicobacter pylori, was quantitated in gastric biopsy specimens from 41 H. pylori-infected patients and during growth in vitro, by quantitative...

  • Helicobacter urease--induced activation of the TLR2/ NLRP3/IL-18 axis protects against asthma. Koch, Katrin N.; Hartung, Mara L.; Urban, Sabine; Kyburz, Andreas; Bahlmann, Anna S.; Lind, Judith; Backert, Steffen; Taube, Christian; Müller, Anne // Journal of Clinical Investigation;Aug2015, Vol. 125 Issue 8, p3237 

    Inflammasome activation and caspase-1--dependent (CASP1-dependent) processing and secretion of IL-1ß and IL-18 are critical events at the interface of the bacterial pathogen Helicobacter pylori with its host. Whereas IL-1ß promotes Th1 and Th17 responses and gastric immunopathology, IL-18...

  • Lack of Association of Helicobacter pylori Infection With Gastric Hypersensitivity or Delayed Gastric Emptying in Functional Dyspepsia. Pootig-Lyul Rhee; Young-Ho Kim; Hee Jung Son; Kim, Jae J.; Kwang Cheul Koh; Seung Woon Paik; Jong Chul Rhee; Kyoo Wan Choi // American Journal of Gastroenterology;Nov1999, Vol. 94 Issue 11, p3165 

    OBJECTIVE: We evaluated the relationship between Helicobacter pylori (H. pylori) infection and gastric sensitivity to distention or gastric emptying rate to define the role of H. pylori in the pathogenesis of functional dyspepsia. METHODS: Gastric barostat, gastric emptying...

  • Answers to Your Questions. Moore, Kent J. // Family Practice Management;Jun2000, Vol. 7 Issue 6, p16 

    Answers questions about family medicine. Code to use for providing allergy shots concocted by an allergist; Patient definition; Testing for helicobacter pylori; Acupuncture and hypnosis; Heel pain diagnosis.

  • Positive Association between Helicobacter pylori Infection and Food Allergy in Children. Corrado, G.; Luzzi, I.; Lucarelli, S.; Frediani, T.; Pacchiarotti, C.; Cavaliere, M.; Rea, P.; Cardi, E. // Journal of Alternative & Complementary Medicine;Jun1999, Vol. 5 Issue 3, p308 

    Presents a study which measured Helicobacter pylori antibodies in the serum of pediatric patients with food allergy, atopic disease and inflammatory bowel disease. Method; Results; Conclusion.

  • Abrogation of oral tolerance to food antigen by H. felis: protective effect of rebamipide. Matysiak-Budnik, T.; Mégraud, F.; Mayo, K.; Moreau, M.; Gaboriau-Routhiau, V.; Heyman, M. // Gut;Sep2002 Supplement 2, Vol. 51, pA22 

    Background: The increase of absorption of intact antigens across the digestive epithelium infected with H. pylori, in vitro and in vivo, may interfere with the regulation of mucosal immune responses and favour development of food allergy. A gastro-protective agent, rebamipide, exerts a positive...

  • Helicobacter Pylori Infection and Gastroesophageal Reflux in Asthmatic Children. Suna Asilsoy; Arzu Babayigit; Duygu Olmez; Nevin Uzuner; Ozkan Karaman; Oguz Oren; Canan Sule Turgut; Dilek Tezcan // Journal of Tropical Pediatrics;Apr2008, Vol. 54 Issue 2, p129 

    The aim of this article is to investigate the prevalence of Helicobacter pylori (HP) infection, frequency of gastroesophageal reflux (GER), existence of atopy and levels of serum immunoglobulin E (IgE) in children with bronchial asthma. One hundred and thirty seven children who were diagnosed as...

  • Journal club: Helicobacter pylori infection in neonatal mice prevents allergic asthma. Ahmad, Nawaid // Thorax;Apr2012, Vol. 67 Issue 4, p301 

    The article presents information on the protection of mice from the allergic airway inflammation and the hyper-responsiveness that are present in allergic asthma through the process testing neonatal infection with helicobacter pylori which is an immonomodulatory pathogen.


Read the Article


Sign out of this library

Other Topics