TITLE

Maternal Insulin Therapy Increases Fetal Endothelial Progenitor Cells During Diabetic Pregnancy

AUTHOR(S)
Fadini, Gian Paolo; Baesso, Ilenia; Agostini, Carlo; Cuccato, Emily; Nardelli, Giovanni Battista; Lapolla, Annunziata; Avogaro, Angelo
PUB. DATE
April 2008
SOURCE
Diabetes Care;Apr2008, Vol. 31 Issue 4, p808
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article reports on the results of a study which found that maternal insulin therapy increases fetal endothelial progenitor cells (EPC) during diabetic pregnancy. It states that EPC played comprehensive role in vascular development and homeostasis. It says that an indirect effect on the fetal environment, possibly through the modulation of maternal and placental metabolism, must be postulated as insulin should not pass the placental barrier.
ACCESSION #
31862971

 

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