Maternal Insulin Therapy Increases Fetal Endothelial Progenitor Cells During Diabetic Pregnancy

Fadini, Gian Paolo; Baesso, Ilenia; Agostini, Carlo; Cuccato, Emily; Nardelli, Giovanni Battista; Lapolla, Annunziata; Avogaro, Angelo
April 2008
Diabetes Care;Apr2008, Vol. 31 Issue 4, p808
Academic Journal
The article reports on the results of a study which found that maternal insulin therapy increases fetal endothelial progenitor cells (EPC) during diabetic pregnancy. It states that EPC played comprehensive role in vascular development and homeostasis. It says that an indirect effect on the fetal environment, possibly through the modulation of maternal and placental metabolism, must be postulated as insulin should not pass the placental barrier.


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