Comprehensive Diabetes Care: The Whole Enchilada

Kuritzky, Louis
March 2008
Internal Medicine Alert;3/29/2008, Vol. 30 Issue 6, p48
The article focuses on a study on diabetics which demonstrated that although glucocentric focus in diabetes produces microvascular benefits, dealing with the factors like blood pressure (BP), lipids, the renin-angiotensin system, and platelets benefits the patient.


Related Articles

  • Renal Perfusion and the Renal Hemodynamic Response to Blocking the Renin System in Diabetes. Lansang, M. Cecilia; Hollenberg, Norman K. // Diabetes;Jul2002, Vol. 51 Issue 7, p2025 

    In three groups of subjects, those with type 2 diabetes and nephropathy, those with type 1 diabetes without nephropathy, and healthy volunteers subjected to short-term hyperglycemia, we observed a counterintuitive relationship. In all three groups, baseline renal plasma flow (RPF) was positively...

  • Renin-angiotensin system activation and interstitial inflammation in human diabetic nephropathy. Mezzano, Sergio; Droguett, Alejandra; Burgos, M. Eugenia; Ardiles, Leopoldo G.; Flores, Claudio A.; Aros, Claudio A.; Carlos, Italo; Vío, Carlos P.; Ruiz-Ortega, Marta; Egido, Jesús // Kidney International Supplement;Oct2003, Issue 86, p64 

    Renin-angiotensin system activation and interstitial inflammation in human diabetic nephropathy. Background. The molecular mechanisms of renal injury in diabetic nephropathy (DN) are not completely understood, although inflammatory cells play a key role. The renin-angiotensin system (RAS) is...

  • Podocyte ACE2 protects against diabetic nephropathy. Harris, Raymond C // Kidney International;Aug2012, Vol. 82 Issue 3, p255 

    As new components of the renin-angiotensin system (RAS) are elucidated, our understanding of the complexities of their interactions also advances. Previous studies have determined that podocytes possess a local RAS that can generate angiotensin II. Podocytes have also been shown to express...

  • Benefits of Renin-Angiotensin Blockade on Retinopathy in Type 1 Diabetes Vary With Glycemic Control. HARINDHANAVUDHI, TASMA; MAUER, MICHAEL; KLEIN, RONALD; ZINMAN, BERNARD; SINAIKO, ALAN; CARAMORI, M. LUIZA // Diabetes Care;Aug2011, Vol. 34 Issue 8, p1838 

    OBJECTIVE--Optimal glycemic control slows diabetic retinopathy (DR) development and progression and is the standard of care for type 1 diabetes. However, these glycemic goals are difficult to achieve and sustain in clinical practice. The Renin Angiotensin System Study (RASS) showed that...

  • Efikasnost valsartana u terapiji perzistentne mikroalbuminurije kod normotenzivnih bolesnika sa tipom 1 Å¡ećerne bolesti. Dragovic, Tamara; Hrvacevic, Rajko; Ajdinovid, Boris; Vujanic, Svetlana // Vojnosanitetski Pregled: Military Medical & Pharmaceutical Journ;Sep/Oct2003, Vol. 60 Issue 5, p555 

    Aim. To determine the efficacy of ATI receptor antagonist (valsartan) in decreasing of urinary excretion of albumin in normotensive patients with type 1 diabetes and incipient diabetic nephropathy (DN). Methods. This was a prospective, randomised, placebo-controlled study, which included 20...

  • Candesartan Cilexetil/Hydrochiorothiazide Treatment in High-Risk Patients with Type 2 Diabetes Mellitus and Microalbuminuria. Ketelhut, Reinhard; Bramlage, Peter // Clinical Drug Investigation;2010, Vol. 30 Issue 5, p301 

    Background: Arterial hypertension complicated by the presence of diabetes mellitus and microalbuminuria is a particularly hazardous risk-factor combination. Blockers of the renin-angiotensin system have been shown to be beneficial with respect to these risk factors in randomized clinical trials....

  • Losartan improves erectile dysfunction in diabetic patients: a clinical trial. Chen, Y; Cui, S; Lin, H; Xu, Z; Zhu, W; Shi, L; Yang, R; Wang, R; Dai, Y // International Journal of Impotence Research;Nov/Dec2012, Vol. 24 Issue 6, p217 

    The activation of cavernous local renin-angiotensin system has an important role in pathogenesis of diabetic erectile dysfunction (ED). In our primary study, we found that angiotensin Type 1 receptor blocker improved the erectile function of diabetic rats. Therefore we explored the losartan in...

  • Blood Pressure Early in Diabetes Depends on a Balance Between Glomerular Filtration Rate and the Renin-Angiotensin System Rojas, Modesto; Bell, Tracy D.; Sturgis, LaShon C.; Springfield, Vanessa; Janardhanan, Rajiv; Fleming, Cassandra; Brands, Michael W. // American Journal of Hypertension;Dec2006, Vol. 19 Issue 12, p1249 

    Onset of diabetes increases plasma renin activity (PRA) and glomerular filtration rate (GFR), but blood pressure (BP) is normal. In this study, a 70% surgical reduction in kidney mass (RK) was used to decrease baseline GFR and to prevent hyperfiltration during diabetes, and angiotensin...

  • Complete Blockade of the Renin-Angiotensin System in Patients With Advanced Diabetic Nephropathy. Deira, Javier; Diaz, Hugo; Grande, Jesús // Diabetes Care;May2003, Vol. 26 Issue 5, p1635 

    Comments on an article by K. Rossing and colleagues on the complete blockade of the renin-angiotensin system in patients with advanced diabetic nephropathy. Study of patients on prior treatment with ACE inhibitors; Calculation of glomerular filtration rate; Decrease in proteinuria and in total...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics