Quantification with HPLC–MS/MS for environmental issues: quality assurance and quality assessment

Bester, Kai
May 2008
Analytical & Bioanalytical Chemistry;May2008, Vol. 391 Issue 1, p15
Academic Journal
The article presents research on the quality of high-performance liquid chromatography with tandem mass spectrometric detection (HPLC-MS/MS) as a tool in environmental chemistry. It is noted that HPLC-MS/MS is the method of choice for quantifying polar compounds such as pesticides and metabolites. According to the author, electrospray ionisation (ESI) and atmospheric pressure chemical ionisation (APCI) are the most popular ionisation mechanisms used. It is concluded that HPLC-MS/MS has become a routine method that offers complementary options.


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