TITLE

Ifosfamide neurotoxicity and potential treatment with methylene blue

AUTHOR(S)
Lohr, Lisa
PUB. DATE
April 2008
SOURCE
Hem/Onc Today;4/25/2008, Vol. 9 Issue 7, p15
SOURCE TYPE
Newspaper
DOC. TYPE
Article
ABSTRACT
The article focuses on neurotoxicity as a side effect of ifosfamide, an agent used in cancer treatment, and its potential treatment with methylene blue. Neurotoxicities symptoms reportedly include delirium, confusion, lethargy and disorientation and stated estimates of incidence center around 10 to 20% of patients treated with ifosfamide. Methylene blue it is shown may reduce symptoms and hasten recovery. A proposed dose of 50-mg given intravenously every four hours is noted.
ACCESSION #
31705845

 

Related Articles

  • Methylthioninium chloride/norepinephrine/vasopressin.  // Reactions Weekly;5/26/2012, Issue 1403, p25 

    The article describes the case of a 47-year-old woman who developed skin necrosis and digital ischaemia after extravasation of methylthioninium chloride while undergoing norepinephrine and vasopressin therapy. Her symptoms included fever, headache, nausea, vomiting and dyspnea. She also...

  • Capecitabine/docetaxel/lapatinib.  // Reactions Weekly;Apr2014, Vol. 1497 Issue 1, p13 

    The article presents a case study of a 66-year-old woman with peripheral neurotoxicity which developed while receiving docetaxel and diarrhoea while receiving capecitabine and lapatinib for advanced breast cancer.

  • Incidence of atypical acute nerve hyperexcitability symptoms in oxaliplatin-treated patients with colorectal cancer. Lucchetta, Marta; Lonardi, Sara; Bergamo, Francesca; Alberti, Paola; Velasco, Roser; Argyriou, Andreas; Briani, Chiara; Bruna, Jordi; Cazzaniga, Marina; Cortinovis, Diego; Cavaletti, Guido; Kalofonos, Haralabos // Cancer Chemotherapy & Pharmacology;Dec2012, Vol. 70 Issue 6, p899 

    Context: Peripheral, acute or chronic, neurotoxicity is one of the main dose-limiting adverse effects of oxaliplatin (OXA). Acute neurotoxicity is typically characterized by distal and perioral cold-induced paresthesias and dysesthesias, but other uncommon symptoms might also be present....

  • Peripheral Neuropathy. Almadrones, Lois // Journal of Gynecologic Oncology Nursing;Winter2006, Vol. 16 Issue 1, p5 

    Focuses on the neurotoxic effects of high dose cisplatin in patients with ovarian cancer. Severity of cancer manifestations in patients; Struggles of medical professionals in the implementation of the 2006 standard of treatment for ovarian cancer; Recognition of ovarian cancer symptoms in the...

  • Methylthioninium chloride.  // Reactions Weekly;11/3/2012, Issue 1426, p32 

    The article describes the case of a 4.5-month-old boy who experienced an anaphylactic-like reaction while receiving methylthioninium chloride.

  • Methylthioninium chloride.  // Reactions Weekly;11/3/2012, Issue 1426, p33 

    The article describes the cases of 34 patients who developed immediate hypersensitivity reactions after receiving a transfusion of methylthioninium chloride.

  • Prilocaine.  // Reactions Weekly;2/28/2009, Issue 1241, p35 

    The article describes the case of a 32-year-old woman who developed methamoglobinaemia while receiving treatment with prilocaine for local anaesthesia. Particular focus is given to her medical history and dosing regimen. She experienced fever, headache and dizziness. Her condition improved after...

  • Duloxetine/methylthioninium chloride interaction.  // Reactions Weekly;11/14/2009, Issue 1278, p16 

    The article describes the case of a 67-year-old man who developed transient encephalopathy and serotonin syndrome after receiving methylthioninium chloride infusion prior to parathyroidectomy and hemithyroidectomy. Duloxetine was also administered to the patient. Particular focus is given to his...

  • Methylthioninium chloride.  // Reactions Weekly;1/12/2013, Issue 1434, p44 

    The article describes the case of a 77-year-old woman who experienced green discolouration of urine following methylthioninium chloride administration to search for a possible fistula.

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics