TITLE

Varicella among Adults: Data from an Active Surveillance Project, 1995—2005

AUTHOR(S)
Marin, Mona; Watson, Tureka L.; Chaves, Sandra S.; Civen, Rachel; Watson, Barbara M.; Zhang, John X.; Perella, Dana; Mascola, Laurene; Seward, Jane F.
PUB. DATE
March 2008
SOURCE
Journal of Infectious Diseases;Mar2008 Supplement 2, Vol. 197, pS94
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
We report detailed population-based data on varicella among adults. In 2 US varicella active surveillance sites with high vaccine coverage among young children, the incidence of varicella among adults declined 74% during 1995-2005. A low proportion (3%) of adults with varicella had been vaccinated, with no improvement over the decade of program implementation, suggesting that the decline was likely secondary to herd-immunity effects. Compared with children, adults had more severe varicella in terms of both clinical presentation and frequency of complications. However, <30% of adults with varicella were treated with acyclovir. Among adolescents, illness severity was intermediate between that in children and adults. Varicella cases are preventable through vaccination. As we enter the second decade of the varicella vaccination program in the United States, we need to ensure that susceptible adolescents and adults are adequately protected from varicella by vaccination and that those who acquire varicella are appropriately treated with effective antiviral treatment.
ACCESSION #
31645377

 

Related Articles

  • Changing Varicella Epidemiology in Active Surveillance Sites—United States, 1995—2005. Guris, Dalya; Jumaan, Aisha O.; Mascola, Laurene; Watson, Barbara M.; Zhang, John X.; Chaves, Sandra S.; Gargiullo, Paul; Perella, Dana; Civen, Rachel; Seward, Jane F. // Journal of Infectious Diseases;Mar2008 Supplement 2, Vol. 197, pS71 

    Significant reductions in varicella incidence were reported from 1995 to 2000 in the varicella active surveillance sites of Antelope Valley (AV), California, and West Philadelphia (WP), Pennsylvania. We examined incidence rates, median age, and vaccination status of case patients for 1995-2005....

  • Safety of Varicella Vaccine after Licensure in the United States: Experience from Reports to the Vaccine Adverse Event Reporting System, 1995—2005. Chaves, Sandra S.; Haber, Penina; Walton, Kimp; Wise, Robert P.; Izurieta, Hector S.; Schmid, D. Scott; Seward, Jane F. // Journal of Infectious Diseases;Mar2008 Supplement 2, Vol. 197, pS170 

    Widespread use of varicella vaccine in the United States could enable detection of rare adverse events not identified previously. We reviewed data from 1995 to 2005 from the Vaccine Adverse Event Reporting System, including data from laboratory analyses, to distinguish adverse events associated...

  • Epidemiology of Varicella in Connecticut, 2001—2005. Sosa, Lynn E.; Hadler, James L. // Journal of Infectious Diseases;Mar2008 Supplement 2, Vol. 197, pS90 

    We analyzed varicella surveillance data in Connecticut for 2001-2005, to describe the epidemiology of varicella in a highly vaccinated population after the introduction of varicella vaccine and to determine the number of preventable cases that had occurred during school-related outbreaks....

  • Varicella Outbreak Epidemiology in an Active Surveillance Site, 1995-2005. Civen, Rachel; Lopez, Adriana S.; Zhang, John; Garcia-Herrera, Jorge; Schmid, D. Scott; Chaves, Sandra S.; Mascola, Laurene // Journal of Infectious Diseases;Mar2008 Supplement 2, Vol. 197, pS114 

    We describe trends and characteristics of varicella outbreaks identified in an active surveillance site from 1995 to 2005. Cases of varicella were reported to the active surveillance project, and outbreaks were defined retrospectively as ⩾5 varicella cases epidemiologically linked to a...

  • Epidemiology of Varicella Hospitalizations in the United States, 1995—2005. Reynolds, Meredith A.; Watson, Barbara M.; Plott-Adams, Kelly K.; Jumaan, Aisha O.; Galil, Karin; Maupin, Teresa J.; Zhang, John X.; Seward, Jane F. // Journal of Infectious Diseases;Mar2008 Supplement 2, Vol. 197, pS120 

    To describe the impact of the varicella vaccination program on varicella-related hospitalizations (VRHs) in the United States, data from the Varicella Active Surveillance Project (VASP) were used to compare rates of hospitalization and rates of complications among patients hospitalized for...

  • Varicella Disease After Introduction of Varicella Vaccine in the United States, 1995-2000. Seward, Jane F.; Watson, Barbara M.; Peterson, Carol L.; Mascola, Laurene; Pelosi, Jan W.; Zhang, John X.; Maupin, Theresa J.; Goldman, Gary S.; Tabony, Laura J.; Brodovicz, Kimberly G.; Jumaan, Aisha O.; Wharton, Melinda // JAMA: Journal of the American Medical Association;2/6/2002, Vol. 287 Issue 5, p606 

    Presents a study to examine population-based disease surveillance data in a number of communities to document the impact of the varicella vaccination program. Context; Objective; Design, setting, and subjects; Main outcome measures; Results; Conclusion that varicella disease has declined in...

  • Knowledge, Attitudes, and Practices Regarding Varicella Vaccination among Health Care Providers Participating in the Varicella Active Surveillance Project, Antelope Valley, California, 2005. Carbajal, Tuna; Civen, Rachel; Reynolds, Meredith; Chaves, Sandra S.; Mascola, Laurene // Journal of Infectious Diseases;Mar2008 Supplement 2, Vol. 197, pS66 

    Knowledge, attitudes, and practices regarding varicella vaccination and disease were assessed among health care providers participating in the Varicella Active Surveillance Project in Antelope Valley, California, in 2005. Compared with those of a similar survey conducted in 1999, results suggest...

  • The Safety Profile of Varicella Vaccine: A 10-Year Review. Galea, Susan A.; Sweet, Ann; Beninger, Paul; Steinberg, Sharon P.; Larussa, Philip S.; Gershon, Anne A.; Sharrar, Robert G. // Journal of Infectious Diseases;Mar2008 Supplement 2, Vol. 197, pS165 

    Varivax (varicella virus vaccine live [Oka/Merck]; Merck), a live attenuated varicella vaccine, is indicated for vaccination against varicella in appropriate individuals ⩾12 months of age. The 10-year safety profile for Varivax is described using data submitted to Merck from routine global...

  • Varicella Outbreak Reporting, Response, Management, and National Surveillance. Leung, Jessica; Rue, Alison; Lopez, Adriana; Ortega-Sanchez, Ismael; Harpaz, Rafael; Guris, Dalya; Seward, Jane F. // Journal of Infectious Diseases;Mar2008 Supplement 2, Vol. 197, pS108 

    Two national surveys were conducted to evaluate the status of varicella case-based surveillance and outbreak response. Although progress toward national surveillance has been significant, a large number of jurisdictions are still without case-based surveillance. For jurisdictions beginning...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics