Smooth Muscle Tumors of the Uterus

Toledo, Gemma; Oliva, Esther
April 2008
Archives of Pathology & Laboratory Medicine;Apr2008, Vol. 132 Issue 4, p595
Academic Journal
Smooth muscle tumors (SMTs) are the most frequent mesenchymal tumors of the uterus. The majority of the uterine SMTs are readily classificable as benign or malignant based on their gross and microscopic appearances. However, when unusual features are seen in some leiomyoma variants, the differential diagnosis with a leiomyosarcoma may become challenging. Moreover, diagnostic criteria for the different subtypes of leiomyosarcoma are not uniform. Finally, non-smooth muscle tumors that originate in the uterus may show overlapping histologic and even immunohistochemical features with uterine SMTs, more commonly with the spindle and epithelioid variants, complicating their correct classification. The diagnosis of malignant uterine SMTs has important prognostic and therapeutic implications. This review provides a practical approach to the diagnosis of uterine leiomyosarcoma based on a systematic assessment of histologic parameters as well as a systematic approach to its differential diagnosis based on histologic and immunohistochemical features.


Related Articles

  • Ovarian Leiomyoma Along with Uterine Leiomyomata: A Common Tumour at an Uncommon Site. GUNASEKARAN, INDIRA; PHANSALKAR, MANJIRI; PALO, LAL BAHADUR; VARGHESE, RENU G'BOY // Journal of Clinical & Diagnostic Research;Nov2015, Vol. 9 Issue 11, p1 

    Ovarian leiomyoma is one of the rarest benign tumours of the ovary, mostly seen in women of reproductive age group. Here we report a case of ovarian leiomyoma as an incidental finding in a patient of 38-year-old woman with uterine leiomyomata. Peroperatively, her left ovary appeared bulky & she...

  • What every black woman should know about fibroid tumors. Walker, Nicole // Ebony;Mar1998, Vol. 53 Issue 5, p54 

    Provides information about fibroid tumors. How fibroids develop in the uterus; Symptoms of fibroids; Causes of fibroids and how they can be prevented; Effects of fibroids; Treatment and alternative medicine for fibroids.

  • ASK LISA CALLAHAN, MD., SELF'S HEALTH EXPERT. Callahan, Lisa // Self;Jan2009, Vol. 31 Issue 1, p74 

    The article provides an answer to a question on what to do when diagnosed with uterine fibroid.

  • A CASE OF BIG FIBROID - DIAGNOSTIC CHALLENGE AND PITFALLS. Mittal, Rita; Sood, Anupa; Sood, Rajeev; Vohra, Rashmi // Indian Obstetrics & Gynaecology;2013, Vol. 3 Issue 4, p36 

    The article presents a case study of a 40-year-old woman diagnosed with leiomyoma of the uterus which may cause morbidity. Topics discussed include an overview of leiomyomas, its diagnosis, its risk factors, its treatment options, and the diagnostic dilemma encountered in the examination. The...

  • Leiomyosarcoma uteri in a white woman. Adesiyun, A. G.; Samaila, M. O. A. // Annals of African Medicine;2010, Vol. 9 Issue 1, p35 

    Sacroma of the corpus uteri should be considered as a differential diagnosis in postmenopausal women presenting with severe abdominal pain, thought to be due to degenerative changes of leiomyoma uteri. We present a rare case of leiomyosacroma in a postmenopausal White woman. Diagnosis was missed...

  • A rapidly growing uterine leiomyoma and postmyomectomy ureteric fistula. Basama, F.; Ghani, R. // Archives of Gynecology & Obstetrics;Jan2007, Vol. 275 Issue 1, p57 

    The article presents a case report of a rapidly growing uterine leiomyoma and postmyomectomy ureteric fistula. A 30-year-old nulliparous woman is presented with acute lower-abdominal pain and a large, tender, pelvi-abdominal mass, reaching the xiphisternum. This report highlights the uncertainty...

  • Magnetic Resonance-Guided Percutaneous Cryoablation of Uterine Fibroids: Early Clinical Experiences. Sakuhara, Yusuke; Shimizu, Tadashi; Kodama, Yoshihisa; Sawada, Akihiro; Endo, Hideho; Abo, Daisuke; Hasegawa, Tenshu; Miyasaka, Kazuo // CardioVascular & Interventional Radiology;Jul/Aug2006, Vol. 29 Issue 4, p552 

    Purpose: Uterine fibroids (leiomyomas) are the most common tumors of the uterus. The present study evaluated the feasibility and effectiveness of magnetic resonance (MR)-guided percutaneous cryoablation for uterine fibroids as a minimally invasive treatment alternative. Methods: From August 2001...

  • Isthmic uterine fibroids: the dynamics of growth. Duhan, Nirmala; Rajotia, Nidhi; Duhan, Urmila; Sangwan, Neetu; Gulati, Natasha; Sirohiwal, Daya // Archives of Gynecology & Obstetrics;Aug2009, Vol. 280 Issue 2, p309 

    The isthmus of uterus is different from the rest of uterus and cervix in anatomic as well as functional aspects. The tumors arising from it may be subjected to a different set of forces which may predispose to growth in a tangential or horizontal direction. A young woman who underwent myomectomy...

  • A Rare Case of Uterine Myxoid Leiomyosarcoma: a Case Report. MITRACHE, Luminita Elena; DUMITRU, Vasile Adrian; SIMION, George; CIRSTOIU, Monica; SAJIN, Maria // Maedica - a Journal of Clinical Medicine;2014, Vol. 9 Issue 3, p269 

    We present the rare case of a 61-year-old female patient who was submitted in the hospital with metrorrhagia and pelvi-abdominal pain. Echographic examination revealed an heterogeneous uterine mass measuring 190/130/110 mm. Therefore, total hysterectomy with bilateral ooforectomy was performed....


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics