TITLE

The dietary supplement 5-hydroxytryptophan and urinary 5-hydroxyindole acetic acid

AUTHOR(S)
Preshaw, Roy M.; Leavitt, Daniel; Hoag, Gordon
PUB. DATE
April 2008
SOURCE
CMAJ: Canadian Medical Association Journal;4/8/2008, Vol. 178 Issue 8, p993
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article presents a medical case involving the dietary supplement 5-Hydroxytrytophan and its association with 5-hydroxindole acetic acid excretion. It states that a 56-year-old woman presented with diarrhea has negative results for ova and parasites in her stool culture. The woman, however, stated that she has been taking a 5-Hydroxytrytophan. The patient was advised to stop taking this supplement. Her diarrhea improved and stopped 6 months later. 5-Hydroxytrytophan is a decarboxylated to serotonin by aromatic L-amino decarboxylase in nervous tissue and the periphery. 5-Hydroxytrytophan from plant sources, usually from the seeds of Griffonia simplicifolia, is promoted and sold by alternative practitioners as a therapy for mild depression and other mood disorders.
ACCESSION #
31495269

 

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