TITLE

Biological control of apatite growth in simulated body fluid and human blood serum

AUTHOR(S)
Juhasz, Judith A.; Best, Serena M.; Auffret, Antony D.; Bonfield, William
PUB. DATE
April 2008
SOURCE
Journal of Materials Science: Materials in Medicine;Apr2008, Vol. 19 Issue 4, p1823
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The surface transformation reactions of bioactive ceramics were studied in vitro in standard K9-SBF solution and in human blood serum (HBS)—containing simulated body fluid (SBF). The calcium phosphate ceramics used for this study were stoichiometric hydroxyapatite (HA), β-tricalcium phosphate (β-TCP) and brushite. Immersion of each calcium phosphate tested in this study, in simulated body fluid, led to immediate surface precipitation of apatite. The use of HBS resulted in a delay in the onset of precipitation and a significant inhibition of the dissolution reaction normally observed for brushite in solution. However, apatite formation still occurred. The use of HBS and SBF in this investigation, which has shown the ability to induce similar crystal growth as that observed in vivo, suggests that there is scope for the use of serum proteins in simulated body fluid in order to create a protein-rich surface coating on biomedical substrates.
ACCESSION #
31244641

 

Related Articles

  • Scientometric Evaluation of Research on Bioceramics. JONG-HEON KIM; KYUNG-RAN NOH; OH-JIN KWON; SUNG-BAE CHOI; SANG-CHEOL KIL // Asian Journal of Chemistry;2014, Vol. 26 Issue 5, p1309 

    During the past several years, there has been a major advance in the development of biomedical materials including various ceramic materials for skeletal repair and reconstruction. To understand bioceramics research trends, we investigated total 12,157 research papers published from 2003 to...

  • Low temperature preparation of calcium phosphate structure via phosphorization of 3D-printed calcium sulfate hemihydrate based material. Suwanprateeb, J.; Suvannapruk, W.; Wasoontararat, K. // Journal of Materials Science: Materials in Medicine;Feb2010, Vol. 21 Issue 2, p419 

    The conversion of newly developed three dimensionally printed calcium sulfate hemihydrate (70–90% wt/wt CaSO4·0.5·H2O) based materials to calcium phosphate bioceramics by phosphorization in di-sodium hydrogen phosphate solution at 80°C for 4, 8, 16 and 24 h was studied. It was...

  • The influence of NO, CH3COO−, and Cl− Ions and the morphology of calcium hydroxyapatite crystals. Stepuk, A. A.; Veresov, A. G.; Putlyaev, V. I.; Tret'yakov, Yu. D. // Doklady Physical Chemistry;Jan2007, Vol. 412 Issue 1, p11 

    The article reports on the synthesis of Calcium hydroxyapatite Ca10 (PO4)6(OH)2(HA) and significant calcium phosphates. The chemical compounds are considered biocompatible materials because HA is the main element of the bones and teeth. Key information regarding the morphology HA crystals are...

  • Chemism of Networking and Biological Functions of Different Types of Phosphate Cements. Jokanović, Vukoman; Živković, Slavoljub // Serbian Dental Journal / StomatoloÅ¡ki Glasnik Srbije;2013, Vol. 60 Issue 1, p32 

    This article provides an overview of calcium phosphate systems used in different formulations of cement mixtures. Chemism of reactions that occur in contact of these systems with water medium shows diversity and specificity of each of selected types of mixtures. As it can be clearly seen from...

  • A new generation of calcium phosphate biomaterials: The role of phase and chemical compositions. Putlyaev, V.; Safronova, T. // Glass & Ceramics;Mar2006, Vol. 63 Issue 3/4, p99 

    Calcium phosphate materials are increasingly applied in the treatment and replacement of bone tissues. The effect of their phase and chemical (ionic) composition on biomedical properties (bioresistivity and bioresorption) of such materials is considered. The principles of the formation of...

  • Fretting wear behavior of calcium phosphate-mullite composites in dry and albumin-containing simulated body fluid conditions. Nath, Shekhar; Ummethala, Raghunandan; Basu, Bikramjit // Journal of Materials Science: Materials in Medicine;Apr2010, Vol. 21 Issue 4, p1151 

    In a recent work, it has been shown that it is possible to achieve a better combination of compressive strength, flexural strength and toughness properties in calcium phosphate (CaP) composites containing 20 and 30 wt% mullite (3Al2O3·2SiO2). In view of their potential application as load...

  • Nanocomposite biomaterials based on hydroxyapatite xerogel. Musskaya, O.; Kulak, A.; Krut'ko, V.; Lesnikovich, L.; Ulasevich, S. // Glass Physics & Chemistry;Oct2011, Vol. 37 Issue 5, p525 

    A hydroxyapatite xerogel with high adsorption-structural characteristics and nanometer-sized crystals has been synthesized using dehydration of a hydroxyapatite gel in air at temperatures of 20-40°C with dehydrating agents, cryogenic treatment (−18 and −196°C), lyophilic...

  • Calcium Deficient Hydroxyapatite for Medical Application Prepared by Hydrothermal Method. Ioku, Koji; Kamitakahara, Masanobu; Ikeda, Tohru // AIP Conference Proceedings;11/25/2010, Vol. 1251 Issue 1, p304 

    Hydrothermal processing plays a key role in the synthesis of biomaterials with excellent biocompatibility in the physiological environment. Especially, calcium phosphates are paid to much attention for the regenerative medicine. Two kinds of porous materials of hydroxyapatite with 70% porosity...

  • Production and Mechanical Properties of Commercial Synthetic Hydroxyapatite (CSHA) Composites. Demirkol, Nermin; Oktar, Faik Nuzhet; Kayali, Eyup Sabri // Key Engineering Materials;2014, Vol. 587, p147 

    Hydroxyapatite (HA), one of the calcium phosphate compounds, is the most widely used bioceramic. HA materials have a common usage in bone repairing due to its ability to accelerate the bone growth around the implant. HA is a biocompatible material and used in production of various kinds of...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics