Automated Identification of Diabetic Retinopathy Stages Using Digital Fundus Images

Nayak, Jagadish; Bhat, P. Subhanna; Acharya U., Rajendra; Lim, C. M.; Kagathi, Manjunath
April 2008
Journal of Medical Systems;Apr2008, Vol. 32 Issue 2, p107
Academic Journal
Diabetic retinopathy (DR) is caused by damage to the small blood vessels of the retina in the posterior part of the eye of the diabetic patient. The main stages of diabetic retinopathy are non-proliferate diabetes retinopathy (NPDR) and proliferate diabetes retinopathy (PDR). The retinal fundus photographs are widely used in the diagnosis and treatment of various eye diseases in clinics. It is also one of the main resources for mass screening of diabetic retinopathy. In this work, we have proposed a computer-based approach for the detection of diabetic retinopathy stage using fundus images. Image preprocessing, morphological processing techniques and texture analysis methods are applied on the fundus images to detect the features such as area of hard exudates, area of the blood vessels and the contrast. Our protocol uses total of 140 subjects consisting of two stages of DR and normal. Our extracted features are statistically significant ( p < 0.0001) with distinct mean ± SD as shown in Table 1. These features are then used as an input to the artificial neural network (ANN) for an automatic classification. The detection results are validated by comparing it with expert ophthalmologists. We demonstrated a classification accuracy of 93%, sensitivity of 90% and specificity of 100%.


Related Articles

  • Diabetic Retinopathy: A Quadtree Based Blood Vessel Detection Algorithm Using RGB Components in Fundus Images. Wasif Reza, Ahmed; Eswaran, C.; Hati, Subhas // Journal of Medical Systems;Apr2008, Vol. 32 Issue 2, p147 

    Blood vessel detection in retinal images is a fundamental step for feature extraction and interpretation of image content. This paper proposes a novel computational paradigm for detection of blood vessels in fundus images based on RGB components and quadtree decomposition. The proposed algorithm...

  • Using multifocal electroretinography hard exudates affect macular function in eyes with diabetic retinopathy. Holm, Kristina; Ponjavic, Vesna; Lövestam-Adrian, Monica // Graefe's Archive of Clinical & Experimental Ophthalmology;Sep2010, Vol. 248 Issue 9, p1241 

    To evaluate the influence of hard exudates on macular function in patients with diabetic retinopathy. Thirty seven eyes from 27 diabetic patients, aged 57 ± 14 years, diabetes duration 12.5 ± 9 years, not previously treated with photocoagulation, underwent fundus photography, multifocal...

  • Do routine eye exams reduce occurrence of blindness from type 2 diabetes? Tubbs, Charles G.; Safeek, Abraham; Mayo, Helen G. // Journal of Family Practice;Sep2004, Vol. 53 Issue 9, p732 

    This article points out that screening eye exams for patients with type 2 diabetes can detect retinopathy early enough so treatment can prevent vision loss. Patients without diabetic retinopathy who are systematically screened by mydriatic retinal photography have a 95 percent probability of...

  • Exudates Detection in Retinal Images using Back Propagation Neural Network. Karegowda, Asha Gowda; Nasiha, Asfiya; Manjunath, A.S.; Jayaram, M. A. // International Journal of Computer Applications;Jul2011, Vol. 25, p25 

    Exudates are one of the primary signs of diabetic retinopathy, which is a main cause of blindness and can be prevented with an early screening process. In this paper, authors have attempted to detect exudates using back propagation neural network. The publicly available diabetic retinopathy...

  • Assessment of Diabetic Retinopathy Using Nonmydriatic Ultra-Widefield Scanning Laser Ophthalmoscopy (Optomap) Compared With ETDRS 7-Field Stereo Photography. KERNT, MARCUS; HADI, INDRAWATI; PINTER, FLORIAN; SEIDENSTICKER, FLORIAN; HIRNEISS, CHRISTOPH; HARITOGLOU, CHRISTOS; KAMPIK, ANSELM; ULBIG, MICHAEL W.; NEUBAUER, ALJOSCHA S. // Diabetes Care;Dec2012, Vol. 35 Issue 12, p2459 

    OBJECTIVE-To compare the diagnostic properties of a nonmydriatic 200° ultra-widefield scanning laser ophthalmoscope (SLO) versus mydriatic Early Treatment of Diabetic Retinopathy Study (ETDRS) 7-field photography for diabetic retinopathy (DR) screening. RESEARCH DESIGN AND METHODS-A...

  • DIABETIC EYE SCREENING IN SIR GANGA RAM HOSPITAL, LAHORE. Adnan, Muhammad; Zafar, Humera; Ali, Zahra; Shabbir, Iffat; Rahat, Tayyaba // Professional Medical Journal;2014, Vol. 21 Issue 5, p941 

    Background: Diabetic retinopathy is the optical complication that may lead to impaired vision. It is one of the most prevalent but preventable blinding disease. Its early diagnosis is prerequisite for the prevention of the visual loss and blindness associated with diabetic complication....

  • A Simple Risk Stratification for Time to Development of Sight-Threatening Diabetic Retinopathy. STRATTON, IRENE M.; ALDINGTON, STEPHEN J.; TAYLOR, DAVID J.; ADLER, AMANDA I.; SCANLON, PETER H. // Diabetes Care;Mar2013, Vol. 36 Issue 3, p580 

    OBJECTIVE -- The American Diabetes Association and the English NHS Diabetic Eye Screening Program recommend annual screening for diabetic retinopathy (DR) with referral to ophthalmology clinics of patients with sight-threatening DR (STDR). Using only longitudinal data from retinal photographs in...

  • Wide-field imaging and OCT vs clinical evaluation of patients referred from diabetic retinopathy screening. Manjunath, V; Papastavrou, V; Steel, D H W; Menon, G; Taylor, R; Peto, T; Talks, J // Eye;Mar2015, Vol. 29 Issue 3, p416 

    PurposeCompare wide-field Optomap imaging and optical coherence tomography (OCT) with clinical examination in diabetic retinopathy (DR).MethodsPatients referred from Diabetic Eye Screening Programmes to three centres underwent dilated ophthalmoscopy and were assigned a DR grade. Wide-field...

  • Signs of diabetic retinopathy.  // Mayo Clinic Guide to Better Vision;2007, p54 

    A chapter from the book "Mayo Clinic Guide to Better Vision" is presented. It discusses the signs and symptoms of diabetic retinopathy. Exudates, which are fatty deposits that appear around the retinal capillary, do not obscure vision unless they develop in the macula. Severe vitreous hemorrhage...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics