Human research review committee requirements in medical journals

Freeman, Scott R.; Lundahl, Kristy; Schilling, Lisa M.; Jensen, J. Daniel; Dellavalle, Robert P.
February 2008
Clinical & Investigative Medicine;Feb2008, Vol. 31 Issue 1, pE49
Academic Journal
Purpose: Independent ethical review committees safeguard participants in human research. The purpose of this study was to describe the current ethical guidelines for human research requirements in the Instructions to Authors of the English language medical journals previously studied in 1995. Methods: The instructions to authors of English language medicine journals from the Abridged Index Medicus were searched for any policies regarding guidance on the ethical treatment of human subjects in research. Results: More medical journals require independent ethics committee approval of human research now [84/101 (83%)] than 10 years ago [48/102 (47%) (P<0.001)], and most journals continue to require that this disclosure appear in the manuscript [71/84 (85%) vs. then 37/48 (77%) (P=0.29)]. Fewer medical journal instructions to authors provide no ethical guidelines for human research now [8/ 101 (8%)] than 10 years ago [25/102 (24%) (P<0.001)]. No journal required submission of the study approval letter or of the approved protocol. Conclusions: Although medicine journals increasingly require disclosure statements of independent ethics committee approval for human research, they fail to verify such approval beyond taking authors for their word.


Related Articles

  • Indian study of women with cervical lesions called unethical. Mudur, Ganapati // BMJ: British Medical Journal (International Edition);04/12/97, Vol. 314 Issue 7087, p1065 

    Questions the ethics of a study conducted by the Indian Council of Medical Research, which observed the natural course of precancerous uterine cervical lesions in women in India. Criticism of the researchers' inability to secure informed consent from the patients; Details of the study; Review of...

  • CNE/CME questions.  // IRB Advisor;Oct2008, Vol. 8 Issue 10, p120 

    A short quiz about the written articles is presented.

  • Introduction. Schrag, Zachary M. // Journal of Policy History;01/01/2011, Vol. 23 Issue 1, p1 

    An introduction to the journal is presented in which the editor discusses various reports published within the issue including one on the evolution of a set of principles for medical experimentation known as the Nuremberg Code, one on the U.S. Public Health Service syphilis study in Guatemala,...

  • The Experimental Use of Human Beings. J.R.E. // Annals of Internal Medicine;Aug66, Vol. 65 Issue 2, p371 

    Editorial. Comments on the endorsement of the Declaration of Helsinki, the code of ethics adopted by the World Medical Association in 1964, by U.S. medical organizations concerned with the care of patients and with clinical investigation. Reasons for the endorsement; Ethical principles that...

  • Paying research subjects: participants' perspectives. Russell, Margaret L.; Moralejo, Donna G.; Burgess, Ellen D. // Journal of Medical Ethics;Apr2000, Vol. 26 Issue 2, p126 

    Objective--To explore the opinions of unpaid healthy volunteers on the payment of research subjects. Design--Prospective cohort. Setting--Southern Alberta, Canada. Participants--Medically eligible persons responding to recruiting advertisements for a randomised vaccine trial were invited to take...

  • The Nuremberg code (1947).  // BMJ: British Medical Journal (International Edition);12/07/96, Vol. 313 Issue 7070, p1448 

    Presents the Nuremberg Code of 1947, ten standards to which physicians must conform when carrying out experiments on human subjects.

  • NIH 'confused' about ethics rules. Rhein, Rex // BMJ: British Medical Journal (International Edition);8/10/91, Vol. 303 Issue 6798, p329 

    Focuses on the confusion on the ethical aspect of regulations and policies for protecting human subjects in experiment. Arguments on the responsibility in rule compliance in the American National Institutes of Health; Effect on the development of AIDS vaccine; Determination of institutional...

  • Ethical issues in research with children and young people. Matutina, Robin E. // Paediatric Nursing;Oct2009, Vol. 21 Issue 8, p38 

    This article, which concentrates largely on literature from the United States, discusses the ethical aspects of research with children, beginning with the historical ill-treatment of children and extending to the present-day protections. Researchers struggle to find the balance that would most...

  • US and UK policies governing research with humans. Maschke, Karen J. // Psychopharmacology;2003, Vol. 171 Issue 1, p47 

    The article examines the U.S. and Great Britain regulatory frameworks governing research with humans. The first part summarizes the main features of each nation's regulatory policies. The article then describes the composition and responsibilities of ethics review committees in the U.S. and...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics