TITLE

Magnesium loss in magnesium deficient subjects with and without physical exercise during prolonged hypokinesia

AUTHOR(S)
Tsiamis, Costas B.; Kakuris, Kostas K.; Deogenov, Viktor A.; Yerullis, Kosmas B.
PUB. DATE
February 2008
SOURCE
Clinical & Investigative Medicine;Feb2008, Vol. 31 Issue 1, pE16
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Objective: To show the effect of hypokinesia (HK; diminished movement) on magnesium (Mg2+) loss in Mg2+ deficient subjects and the effect of physical exercise and on Mg2+ deficiency with and without physical exercise: Mg2+ balance, serum Mg2+ concentration and Mg2+ loss were measured. Methods: Studies were conducted on 30 healthy male volunteers during a pre-experimental period of 30 days and an experimental period of 364 days. They were divided equally into three-groups: unrestricted active control subjects (UACS), continuous hypokinetic subjects (CHKS) and periodic hypokinetic subjects (PHKS). The UACS group ran average distances of 9.3 ± 1.2 km.day-1; the CHKS group walked average distances of 0.9 ±0.2 km.day-1; and the PHKS group walked and ran average distances of 0.9 ± 0.2 km and 9.3 ± 1.2 km.day-1 for 5-and 2-days per week, respectively. Results: Mg2+deficiency, serum Mg2+ level, fecal and urine Mg2+ loss increased (P < 0.05), in the PHKS and CHKS groups compared with their pre-experimental values and the values in the UACS group. However, serum Mg2+ concentration, urine and fecal Mg2+ loss and Mg2+ deficiency increased more (P < 0.05) in the PHKS group than in the CHKS group. Conclusions: Mg2+ deficiency is more evident with than without physical exercise and Mg2+ loss is exacerbated more with higher than lower Mg2+ deficiency. This indicates that Mg2+ deficiency with and without physical exercise and Mg2+ loss with higher and lower Mg2+ deficiency is due to inability of the body to use Mg2+ and more so when physically healthy subjects are submitted to prolonged periodic than continuous hypokinesia.
ACCESSION #
31198404

 

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