Peutz-Jegher syndrome

Flutter, Laura
February 2008
Archives of Disease in Childhood;Feb2008, Vol. 93 Issue 2, p163
Academic Journal
The article reports on the study conducted on a 14-year-old girl with Peutz-Jegher syndrome (PJS) in Great Britain. She was admitted to the hospital because of acute abdomen of unknown cause. After investigation, physicians found that she has iron deficiency anaemia and she denied a history of menorrhagia and she is not vegetarian. Laparotomy was conducted and an intussusception was discovered with diffused small bowel ischaemia. Further examinations were done on the patient and it showed that she had PJS syndrome. It is a rare autosomal dominant condition resulting in hematomatous polyps of the GI tract, sporadic mutation accounts for 50% of cases.


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