TITLE

Early onset of treatment effects with oral risperidone

AUTHOR(S)
Raedler, Thomas J.; Schreiner, Andreas; Naber, Dieter; Wiedemann, Klaus
PUB. DATE
January 2007
SOURCE
BMC Psychiatry;2007, Vol. 7, p4
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Background: The dogma of a delayed onset of antipsychotic treatment effects has been maintained over the past decades. However, recent studies have challenged this concept. We therefore performed an analysis of the onset of antipsychotic treatment effects in a sample of acutely decompensated patients with schizophrenia. Methods: In this observational study, 48 inpatients with acutely decompensated schizophrenia were offered antipsychotic treatment with oral risperidone. PANSS-ratings were obtained on day 0, day 1, day 3, day 7 and day 14. Results: Significant effects of treatment were already present on day 1 and continued throughout the study. The PANSS positive subscore and the PANSS total score improved significantly more than the PANSS negative subscore. Conclusion: Our results are consistent with the growing number of studies suggesting an early onset of antipsychotic treatment effects. However, non-pharmacological effects of treatment also need to be taken into consideration.
ACCESSION #
29962921

 

Related Articles

  • Schizophrenia and Employment: Evaluation From Professionals Point of View. Zaprutko, Tomasz; Kus, Krzysztof; Bilobryvka, Rostyslav; Rakhman, Lyudmyla; Göder, Robert; Michalak, Michał; Pogłodziński, Andrzej; Nowakowska, Elżbieta // Psychiatric Quarterly;Dec2015, Vol. 86 Issue 4, p569 

    Schizophrenia is a severe and chronic disorder requiring long-lasting and comprehensive treatment. Because of this disorder patients are socially isolated. Consequently, schizophrenia has a significant economic burden both in a group of direct and indirect costs. The aim was to analyse experts'...

  • Economic evaluations of olanzapine and risperidone. Shaw, James W. // American Journal of Health-System Pharmacy;7/15/2002, Vol. 59 Issue 14, p1366 

    Presents an economic analysis comparing olanzapine and risperidone for treating schizophrenia. Overview of the disease; Costs of schizophrenia; Methods of economic evaluation; Results of randomized clinical trials.

  • Medication Treatment Patterns following Initiation on Olanzapine versus Risperidone: A Retrospective Analysis. Zhao, Z.; Tunis, S.L.; Lage, M.J. // Clinical Drug Investigation;2002, Vol. 22 Issue 11, p741 

    Objective: To compare medication treatment patterns for patients with schizophrenia following initiation on olanzapine versus risperidone. Methods: Retrospective analysis of a large, geographically diverse claims database of insured individuals identified 670 enrollees who: (1) were diagnosed...

  • A transcranial magnetic stimulation study of the effects of olanzapine and risperidone on motor cortical excitability in patients with schizophrenia. Fitzgerald, Paul B.; Brown, Timothy L.; Daskalakis, Jeff Z.; Kulkarni, J. // Psychopharmacology;2002, Vol. 162 Issue 1, p74 

    Rationale: There has been a progressive increase in interest in the functioning of the main inhibitory and excitatory neurotransmitters in the pathophysiology of schizophrenia. Limited information is available as to how these neurotransmitters are affected by commonly prescribed antipsychotic...

  • Comparison of prolactin concentrations between haloperidol and risperidone treatments in the same female patients with schizophrenia. Yasui-Furukori, Norio; Kondo, Tsuyoshi; Suzuki, Akihito; Mihara, Kazuo; Kaneko, Sunao // Psychopharmacology;2002, Vol. 162 Issue 1, p63 

    The present study aimed to investigate intraindividual changes in plasma prolactin concentrations by switching from haloperidol treatment to risperidone treatment. The subjects were 15 female schizophrenic inpatients who received firstly haloperidol 12 mg/day for at least 2 weeks and,...

  • Risperidone.  // Reactions Weekly;1/12/2013, Issue 1434, p56 

    The article describes the cases of two patients who received risperidone for schizophrenia and major depressive disorder, respectively, but they developed rabbit syndrome during treatment.

  • Olanzapine versus risperidone. A prospective comparison of clinical and economic outcomes in schizophrenia. Edgell, E.T.; Andersen, S.W.; Johnstone, B.M.; Dulisse, B.; Revicki, D.; Breier, A. // PharmacoEconomics;2000, Vol. 18 Issue 6, p567 

    Objective: To compare the clinical and economic outcomes associated with olanzapine and risperidone treatment for schizophrenia.Design and Setting: An international, multicentre, double-blind, prospective study. To facilitate economic comparisons, our sample was...

  • Risperidone.  // Reactions Weekly;7/24/2010, Issue 1311, p36 

    The article describes the case of a girl who developed tardive writer's cramp while receiving risperidone to treat schizophrenia.

  • Treatment Refractory Schizophrenia. Lindemayer, Jean-Pierre // Psychiatric Quarterly;Dec2000, Vol. 71 Issue 4, p373 

    Treatment resistance constitutes a significant dilemma in schizophrenia since it affects a substantial number of patients, their families and the health care professionals involved in their care. Nonresponsiveness needs to be approached as a multidimensional syndrome by specifying which symptoms...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics