Don't tell Stephen O'Rahilly that losing weight is just a matter of willpower

Shell, Ellen Ruppell
May 2000
Discover;May2000, Vol. 21 Issue 5, p66
Discusses the genetic aspects of obesity. Influence of an individual's genetic composition on his eating behavior; Importance of the gene leptin in regulating appetite; Scientific facts supporting the role of genetics in human nutrition.


Related Articles

  • Greedy gene dooms dieting.  // Filipino Post;11/25/2010, p5 

    The article presents a study on the association between genes and dieting in which it shows that fat mass and obesity associate (FTO) rogue gene boosts the appetite of an individual which leads to obesity.

  • Power of maximum HLOD tests to detect linkage to obesity genes. Yun Joo Yoo; Yanling Huo; Yuming Ning; Gordon, Derek; Finch, Stephen; Mendell, Nancy R. // BMC Genetics;2003 Supplement 1, Vol. 4, pS16 

    Background: We investigate the power of heterogeneity LOD test to detect linkage when a trait is determined by several major genes using Genetic Analysis Workshop 13 simulated data. We consider three traits, two of which are disease-causing traits: 1) the rate of change in body mass index (BMI);...

  • End Fattism.  // Technology Review;Jul2005, Vol. 108 Issue 7, p18 

    This article focuses on a study being conducted by Rockefeller University molecular geneticist and obesity researcher Jeffrey Friedman about the genetic aspect of obesity. According to Friedman, obesity is a disorder that is largely caused by genetic factors. For more than a decade, Friedman has...

  • Gıda Bağıml&305;lığı. Öncü, Gülay; Karakaya, Sibel // Academic Food Journal / Akademik GIDA;oca-mar2013, Vol. 11 Issue 1, p97 

    Obesity is one of the most important health problems in developed and developing countries nowadays. The increasing prevalence of obesity has pioneered research about preventing obesity and investigation of the cause of obesity worldwide. Besides genetic and environmental factors, nutrition...

  • Unaltered TNF-α production by macrophages and monocytes in diet-induced obesity in the rat. Bedoui, Sammy; Velkoska, Elena; Bozinovski, Steve; Jones, Jessica E.; Anderson, Gary P.; Morris, Margaret J. // Journal of Inflammation;2005, Vol. 2, p2 

    Background: Recent findings have established an association between obesity and immune dysfunction. However, most of the studies investigating the effects of obesity on immune function have been carried out in genetically obese rodent models. Since human obesity is mostly due to intake of a high...

  • DON'T BLAME GENETICS.  // Joe Weider's Muscle & Fitness;Jun2009, Vol. 70 Issue 6, p46 

    The article focuses on the findings of researchers in Finland on the genetic aspects of obesity. The researchers claim that though some genetic condition do lead to obesity, but regular exercise can overcome genetic aspects to prevent wait gain. The research, that was conducted on 150 pair of...

  • Segregation Analysis of Overweight Body Condition in an Experimental Cat Population. Häring, Thomas; Wichert, Brigitta; Dolf, Gaudenz; Haase, Bianca // Journal of Heredity;Jan2011 Supplement 1, Vol. 102, pS28 

    The goal of this study was to analyze the mode of inheritance of an overweight body condition in an experimental cat population. The cat population consisted of 95 cats of which 81 cats could be clearly classified into lean or overweight using the body condition scoring system according to...

  • Genetics of obesity: an overview of current approaches and advancement. Helali, Asadul Mazid; Iti, Farhana Matin; Ismail, Salwani; Haque, Mainul // Journal of Applied Pharmaceutical Science;Oct2013, Vol. 3 Issue 10, p1 

    Elucidation of obesity susceptibility genes through genome wide approaches as well as candidate gene approaches provides great promise in ultimately determining the genetic underpinnings of obesity. The complex nature of human obesity stems from the multiple interaction of several genes that...

  • Induction of TDO2 and IDO2 in Liver by High-Fat Feeding in Mice: Discrepancies with Human Obesity. Poulain-Godefroy, Odile; Eury, Elodie; Leloire, Audrey; Hennart, Benjamin; Guillemin, Gilles J.; Allorge, Delphine; Froguel, Philippe // International Journal of Tryptophan Research;2013 Supplement, Issue 6, p29 

    Low-grade and chronic inflammation is elicited in white adipose tissue in human obesity. The presence of inflammatory molecules leads to an increased tryptophan catabolism through the induction of indoleamine-2,3-dioxygenase-1 (IDO1). In order to characterize the mechanisms underlying this...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics