Dilution of the 75-g oral glucose tolerance test increases postprandial glycemia: implications for diagnostic criteria

Sievenpiper, John L.; Jenkins, David J.A.; Josse, Robert G.; Vuksan, Vladimir
April 2000
CMAJ: Canadian Medical Association Journal;4/04/2000, Vol. 162 Issue 7, p993
Academic Journal
Discusses how dilution has been noticed to increase the glycemic response to various sugars, including glucose. Assessment of the effect of diluting a 75 gram oral glucose tolerance test (OGTT) on two-hour postprandial blood glucose-based diagnostic outcomes, incremental glycemia and area under the glucose curve; Background; Methods; Results; Interpretation.


Related Articles

  • The Relationship of Fasting Plasma Glucose Values and Other Variables to 2-h Postload Plasma Glucose in Japanese Subjects. Bando, Yukihiro; Ushiogi, Yasuyuki; Okafuji, Kazuhiro; Toya, Daisyu; Tanaka, Nobuyoshi; Fujisawa, Masakiyo // Diabetes Care;Jul2001, Vol. 24 Issue 7, p1156 

    Presents a study which investigated the relationship between fasting plasma glucose values and other variables to 2-h post-75-g oral glucose load glycemia in Japanese subjects. Research design and methods; Results; Conclusions.

  • Hypoglycemia: Separating facts from fads. Cerrato, Paul L. // RN;Apr89, Vol. 52 Issue 4, p81 

    Provides information on nursing patients with hypoglycemia. Facts on how blood sugar develops; Information on interpreting glucose tolerance tests; Suggestions on caring for hypoglycemics. INSET: Interpreting the glucose tolerance test.

  • The Significance of Impaired Fasting Glucose Versus Impaired Glucose Tolerance. Schianca, Gian Piero Carnevale; Rossi, Antonello; Sainaghi, Pier Paolo; Maduli, Elisabetta; Bartoli, Ettore // Diabetes Care;May2003, Vol. 26 Issue 5, p1333 

    OBJECTIVE — The American Diabetes Association recommended substituting 2hBS (glycemia at the second hour of an oral glucose tolerance test [OGTT]) for fasting blood glucose (FBS) in screening for glucose intolerance. It is debated whether these tests measure the same abnormality and...

  • Assessing the Shape of the Glucose Curve During an Oral Glucose Tolerance Test. Tschritter, Otto; Fritsche, Andreas; Shirkavand, Fatemeh; Machicao, Fausto; Häring, Hans; Stumvoll, Michael // Diabetes Care;Apr2003, Vol. 26 Issue 4, p1026 

    OBJECTIVE — The oral glucose tolerance test (OGTT) is used to define the status of glucose tolerance based on the plasma glucose level at 120 min. The purpose of the present study was to identify parameters that determine the shape of the plasma glucose course measured at 0, 30, 60, 90,...

  • Understated data value.  // MLO: Medical Laboratory Observer;Dec2003, Vol. 35 Issue 12, p7 

    Presents a letter to the editor concerning the usefulness of oral glucose tolerance test. Measurement of the fasting plasma glucose.

  • Improvement in glucose tolerance due to Momordica charantia (karela). Leatherdale, B.A.; Panesar, R.K.; Singh, G.; Atkins, T.W.; Bailey, C.J.; Bignell, A.H.C. // British Medical Journal (Clinical Research Edition);6/6/1981, Vol. 282 Issue 6279, p1823 

    Examines the effectiveness of Momordica charantia (karela) fruit in treating diabetes, leprosy, jaundice, rheumatism and gout. Reduction on blood glucose concentrations in the diabetics; Improvement in glucose tolerance; Details on the insulin concentrations with karela.

  • Fasting Versus Postload Glucose Levels. Gerstein, Hertzel C. // Diabetes Care;Nov2001, Vol. 24 Issue 11, p1855 

    Compares the effectiveness of diagnosing diabetes and impaired glucose tolerance (IGT) using fasting and postload glucose levels. Diagnostic thresholds for diabetes and IGT: Importance of early diagnosis of both disorders; Value of fasting glucose data.

  • Resolving the Sources of Plasma Glucose Excursions following a Glucose Tolerance Test in the Rat with Deuterated Water and [U-13C]Glucose. Delgado, Teresa C.; Barosa, Cristina; Nunes, Patr�cia M.; Cerd�n, Sebasti�n; Geraldes, Carlos F. G. C.; Jones, John G. // PLoS ONE;Mar2012, Vol. 7 Issue 3, p1 

    Sources of plasma glucose excursions (PGE) following a glucose tolerance test enriched with [U-13C]glucose and deuterated water were directly resolved by 13C and 2H Nuclear Magnetic Resonance spectroscopy analysis of plasma glucose and water enrichments in rat. Plasma water 2H-enrichment...

  • Diagnosing Diabetes With Glucose Criteria: Worshipping a False God. DAVIDSON, MAYER B. // Diabetes Care;Feb2011, Vol. 34 Issue 2, p524 

    The author discusses the actual evidence upon which the current glucose criteria for diagnosing diabetes mellitus is based. According to the author, the relationship among the microvascular complications of diagnosis, glucose concentrations, and A1C levels is an evidence that glucose criteria...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics