Zubkowicz, Marta; Chojnowski, Krzysztof
December 2007
Problemy Terapii Monitorowanej;dec2007, Vol. 18 Issue 4, p245
Academic Journal
Recombinant activated factor VII (rFVIIa; NovoSeven, NovoNordisk, Dennmark) was originally developed for the treatment of patients with haemophilia A and haemophilia B with inhibitory antibodies against factor VIII or factor IX. It has been approved in Europe for the treatment of haemorrhage in inherited factor VII deficiency and Glanzmann's thrombasthenia with platelet antibodies and refractory to platelet transfusions. In recent years, rFVIIa has also been employed for the management of uncontrolled bleeding in a number of congenital and acquired hemostatic abnormalities.


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