Identifying dyspepsia in the Greek population: translation and validation of a questionnaire

Anastasiou, Foteini; Antonakis, Nikos; Chaireti, Georgia; Theodorakis, Pavlos N.; Lionis, Christos
January 2006
BMC Public Health;2006, Vol. 6 Issue 1, p56
Academic Journal
Background: Studies on clinical issues, including diagnostic strategies, are considered to be the core content of general practice research. The use of standardised instruments is regarded as an important component for the development of Primary Health Care research capacity. Demand for epidemiological cross-cultural comparisons in the international setting and the use of common instruments and definitions valid to each culture is bigger than ever. Dyspepsia is a common complaint in primary practice but little is known with respect to its incidence in Greece. There are some references about the Helicobacter Pylori infection in patients with functional dyspepsia or gastric ulcer in Greece but there is no specific instrument for the identification of dyspepsia. This paper reports on the validation and translation into Greek, of an English questionnaire for the identification of dyspepsia in the general population and discusses several possibilities of its use in the Greek primary care. Methods: The selected English postal questionnaire for the identification of people with dyspepsia in the general population consists of 30 items and was developed in 1995. The translation and cultural adaptation of the questionnaire has been performed according to international standards. For the validation of the instrument the internal consistency of the items was established using the alpha coefficient of Chronbach, the reproducibility (test - retest reliability) was measured by kappa correlation coefficient and the criterion validity was calculated against the diagnosis of the patients' records using also kappa correlation coefficient. Results: The final Greek version of the postal questionnaire for the identification of dyspepsia in the general population was reliably translated. The internal consistency of the questionnaire was good, Chronbach's alpha was found to be 0.88 (95% CI: 0.81-0.93), suggesting that all items were appropriate to measure. Kappa coefficient for reproducibility (test - retest reliability) was found 0.66 (95% CI: 0.62-0.71), whereas the kappa analysis for criterion validity was 0.63 (95% CI: 0.36-0.89). Conclusion: This study indicates that the Greek translation is comparable with the English-language version in terms of validity and reliability, and is suitable for epidemiological research within the Greek primary health care setting.


Related Articles

  • Randomised controlled trial of Helicobacter pylori testing and endoscopy for dyspepsia in primary care. Delaney, B C; Wilson, S; Roalfe, A; Roberts, L; Redman, V; Wearn, A; Hobbs, F D R // BMJ: British Medical Journal (International Edition);04/14/2001, Vol. 322 Issue 7291, p898 

    Conclusions: The test and endoscopy strategy increases endoscopy rates over usual practice in primary care. The additional cost is not offset by benefits in symptom relief or quality of life.

  • NICE guidelines on dyspepsia. Baines, Emma // GP: General Practitioner;11/3/2003, p12 

    NICE will recommend a test-and-treat strategy for uncomplicated dyspepsia next spring, but the management of people over 55 years of age could be different. According to the draft guidelines, general practitioners should only refer patients for endoscopy if they have alarm symptoms such as...

  • Outcomes of Initial Noninvasive Helicobacter pylori Testing in U.S. Primary Care Patients With Uninvestigated Dyspepsia. Ladabaum, Ufi; Fendrick, A. Mark; Scheiman, James M. // American Journal of Gastroenterology;Jul2001, Vol. 96 Issue 7, p2051 

    OBJECTIVE: Recent European trials demonstrate that testing and treatment for Helicobacter pylori (H. pylori) is an effective alternative to prompt endoscopy in uninvestigated dyspepsia. The eventual endoscopy rate after H. pylori testing, which is a key determinant of...

  • EVALUATION OF Helicobacter pylory COLONIZATION BY SEROLOGIC TEST (IgG) AND DYSPEPSIA IN VOLUNTEERS FROM THE COUNTRYSIDE OF MONTE NEGRO, IN THE BRAZILIAN WESTERN AMAZON REGION. Ribeiro, Rafael Bernardon; Martins, Herlon Saraiva; dos Santos, Vera Aparecida; EL Khouri, Marcelo; Duarte, Leandro Savoy; Burattini, Marcelo Nascimento; Cordeiro, Quirino; Camargo, Luiz Marcelo Aranha; Corbett, Carlos Eduardo Pereira // Revista do Instituto de Medicina Tropical de Sao Paulo;jul2010, Vol. 52 Issue 4, p203 

    The present study intended to analyze the seroprevalence of Helicobacter pylori, IgG, and its relation to dyspepsia in a population from the western Amazon region. During the “Projeto Bandeira Científica”, a University of São Paulo Medical School program, in Monte...

  • Test-and-Treat Strategy for Dyspepsia Is Supported. Walling, Anne D. // American Family Physician;8/15/2002, Vol. 66 Issue 4, p660 

    Presents an abstracts of studies on dyspepsia. 'Treating Helicobacter pylori in Primary Care Patients With Uninvestigated Dyspepsia: The Canadian Adult Dyspepsia Empiric Treatment--Helicobacter pylori Positive (CADET-Hp) Randomised Controlled Trial,' by N. Chiba et al., from the April 27, 2002...

  • TREATMENT OF HELICOBACTER PYLORI INFECTION IN FUNCTIONAL DYSPEPSIA. Grimm, Kenneth J. // Journal of Family Practice;Jul1999, Vol. 48 Issue 7, p496 

    The article cites a research study that examines whether Helicobacter pylori eradication is an effective treatment for patients with functional or nonulcer dyspepsia. Dyspepsia in the absence of peptic ulcer disease is a very common condition in primary care patients. Approximately 50% of these...

  • Helicobacter pylori related dyspepsia: prevalence and treatment outcomes at University Kebangsaan Malaysia-Primary Care Centre. Aziz, Aznida Firzah Abdul; Hamzah, Zuhra; Seng Fah Tong; Nadeson, Sukumar; Wan Puteh, Sharifa Ezat // Asia Pacific Family Medicine;2009, Vol. 8, Special section p1 

    Background: Optimum management of dyspepsia in primary care is a debatable subject. Testing for Helicobacter pylori (HP) has been recommended in primary care as this strategy will cure most underlying peptic ulcer disease and prevent future gastro duodenal disease. Methods: A total of 98...

  • Limited impact on endoscopy demand from a primary care based 'test and treat' dyspepsia management strategy: the results of a randomised controlled trial. Shaw, Ian S.; Valori, Roland M.; Charlett, André; McNulty, Cliodna A. M. // British Journal of General Practice;May2006, Vol. 56 Issue 526, p369 

    Background Helicobacter pylori testing has been suggested as an alternative to endoscopy for young patients with dyspepsia. Secondary care studies have suggested that demand for endoscopy among this group could be reduced by up to 74%. However, the effect of H. pylori testing in the prirnary...

  • BENIGN UPPER GASTROINTESTINAL DISEASE.  // Gut;Feb2007 Supplement 1, Vol. 56, p27 

    The article discusses several upper gastrointestinal (GI) diseases and their rate of prevalence in Great Britain, and offers several recommendations for their effective management. Several GI related diseases including gastro-oesophageal reflux disease, helicobacter pylori infection, and...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics