Factors associated with a measles outbreak in children admitted at Mahosot Hospital, Vientiane, Laos

Mayxay, Mayfong; Khomthilat, Tiengthong; Souvannasing, Phoutthalavanh; Phounesavath, Khamphouvanh; Vorasane, Banlieng; Keomany, Sommay; Douangdala, Phouvieng; Philavong, Khamseng; Srour, Leila; Newton, Paul N.
January 2007
BMC Public Health;2007, Vol. 7 Issue 1, p193
Academic Journal
Background: In 2002 and 2003 there were large outbreaks of measles in many provinces of Laos, including in Vientiane. We therefore conducted a study to determine risk factors associated with measles amongst children admitted at Mahosot Hospital, Vientiane. Methods: A retrospective case-control study was conducted in 50 children with clinical measles who were matched by age and sex with 50 healthy children (who had never had a febrile rash) living in the same villages as the cases. Results: The proportion of children with complete immunizations was significantly lower in the group with clinical measles compared to the controls [13/50 (26%) vs 34/50 (68%), P < 0.001). The percentage of children who had received measles vaccine at 9-23 months of age was significantly lower in the group with clinical measles compared to the healthy controls [12/50 (24%) vs 24/50 (48%), P = 0.01). The family educational and socio-economic status did not differ significantly (P > 0.05) between cases and controls. Conclusion: These results emphasize the importance of intensification of measles immunization coverage in Laos. The strengthening of campaigns with large, widespread high second dose coverage is likely to be a key measure to prevent further measles outbreaks in Laos (192 words).


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