Cohort differences in disease and disability in the young-old: findings from the MRC Cognitive Function and Ageing Study (MRC-CFAS)

Jagger, Carol; Matthews, Ruth J.; Matthews, Fiona E.; Spiers, Nicola A.; Nickson, Judith; Paykel, Eugene S.; Huppert, Felicia A.; Brayne, Carol
January 2007
BMC Public Health;2007, Vol. 7 Issue 1, p156
Academic Journal
Background: Projections of health and social care need are highly sensitive to assumptions about cohort trends in health and disability. We use a repeated population-based cross-sectional study from the Cambridgeshire centre of the UK Medical Research Council Cognitive Function and Ageing Study to investigate trends in the health of the young-old UK population Methods: Non-overlapping cohorts of men and women aged 65-69 years in 1991/2 (n = 689) and 1996/7 (n = 687) were compared on: self-reported diseases and conditions; self-rated health; mobility limitation; disability by logistic regression and four-year survival by Cox Proportional Hazards Regression models, with adjustments for differences in socio-economic and lifestyle factors. Results: Survival was similar between cohorts (HR: 0.91, 95% CI: 0.62 to 1.32). There was a significant increase in the number of conditions reported between cohorts, with more participants reporting 3 or more conditions in the new cohort (14.2% vs. 10.1%). When individual conditions were considered, there was a 10% increase in the reporting of arthritis and a significant increase in the reporting of chronic airways obstruction (OR: 1.36, 95% CI: 1.04 to 1.78). Conclusion: This study provides evidence of rising levels of ill-health, as measured by the prevalence of self-reported chronic conditions, in the newer cohorts of the young-old. Though changes in diagnosis or reporting of disease cannot, as yet, be excluded, to better understand whether our findings reflect real increases in ill-health, investment should be made into improved population-based databases, linking self-report and objective measures of health and function, and including those in long-term care.


Related Articles

  • Improvements in readiness to change and drinking in primary care patients with unhealthy alcohol use: a prospective study. Bertholet, Nicolas; Horton, Nicholas J.; Saitz, Richard // BMC Public Health;2009, Vol. 9 Issue 1, p1 

    Background: The course of alcohol consumption and cognitive dimensions of behavior change (readiness to change, importance of changing and confidence in ability to change) in primary care patients are not well described. The objective of the study was to determine changes in readiness,...

  • Complexity of lifetime occupation and cognitive performance in old age. Correa Ribeiro, P. C.; Lopes, C. S.; Lourenço, R. A. // Occupational Medicine;Dec2013, Vol. 63 Issue 8, p556 

    Background Occupation is recognized as a modifiable factor related to cognitive reserve in older adults. Aims To examine the association between levels of complexity in lifelong occupations and cognitive performance in later life. Methods A cross-sectional study of older adult users (aged 65 or...

  • All Internal in the Family? Koch, Thomas G. // Journal of Human Resources;Fall2015, Vol. 50 Issue 4, p959 

    Measurements of the impact of public health insurance have typically focused on the health and insurance outcomes of the newly eligible child. In this paper, I investigate the consequences of public health insurance for the other members of the household. Using a regression discontinuity design,...

  • Apolipoprotein E Genotype Modifies the Association between Midlife Lung Function and Cognitive Function in Old Age. Giltay, Erik J.; Nissinen, Aulikki; Giampaoli, Simona; Kromhout, Daan // Dementia & Geriatric Cognitive Disorders;2009, Vol. 28 Issue 5, p433 

    Background/Aims: Because poor lung function may be a risk factor for cognitive decline, we aimed to test the association of respiratory function with cognitive function and dementia later in life, as well as potential effect modification by APOE ε4 carrier status. Methods: In a prospective...

  • Key determinants of induced abortion in women seeking postabortion care in hospital facilities in Ouagadougou, Burkina Faso. Ilboudo, Patrick G. C.; Somda, Serge M. A.; Sundby, Johanne // International Journal of Women's Health;2014, Vol. 6, p565 

    Introduction: Despite the universal recognition of unsafe abortion as a major public health problem, very little research has been conducted to document its precipitating factors in Burkina Faso. Our aim was to investigate the key determinants of induced abortion in a sample of women who sought...

  • Complementary And Alternative Medicine Use among American Women: Findings from The National Health Interview Survey, 2002. Upchurch, Dawn M.; Chyu, Laura; Greendale, Gail A.; Utts, Jessica; Bair, Yali A.; Zhang, Guili; Gold, Ellen B. // Journal of Women's Health (15409996);Jan2007, Vol. 16 Issue 1, p102 

    Background: The prevalence of use of complementary and alternative medicine (CAM) among Americans is high, especially among women, but a national profile of women CAM users has yet to be characterized. This study identified sociodemographic, health, and lifestyle factors associated with use of...

  • Overweight and Obesity in Sexual-Minority Women: Evidence From Population-Based Data. Boehmer, Ulrike; Bowen, Deborah J.; Bauer, Greta R. // American Journal of Public Health;Jun2007, Vol. 97 Issue 6, p1134 

    Objective. We sought to determine whether lesbians have higher rates of overweight and obesity than women of other sexual orientations. Methods. We compared population estimates of overweight and obesity across sexual orientation groups, using data from the 2002 National Survey of Family Growth....

  • The Minnesota Women Healthy Aging Project. Georgopoulos, Apostolos P. // Minnesota Medicine;Jan2012, Vol. 95 Issue 1, p49 

    The Minnesota Women Healthy Aging Project is an effort to understand how the brain changes with age and why some brains are more resilient than others. Using a unique meth-odology, researchers are evaluating the brain status of a number of women by taking multi-ple, multimodal measurements and...

  • Good Health Status of Rural Women in the Reproductive Ages. Bourne, Paul Andrew; Rhule, Joan // International Journal of Collaborative Research on Internal Medi;Jul2009, Vol. 1 Issue 5, p132 

    Background: Women are traditionally over represented among the poor and therefore in the long run, have less access to remuneration and health resources, including health insurance and social security services. Women are disadvantaged on some fundamental economic indicators such as unemployment...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics