TITLE

Can current national surveillance systems in England and Wales monitor sexual transmission of hepatitis C among HIV-infected men who have sex with men?

AUTHOR(S)
Dougan, Sarah; Balogun, M. Adekoyejo; Elford, Jonathan; Brant, Lisa J.; Sinka, Katy; Evans, Barry G.; Ramsay, Mary E.
PUB. DATE
January 2007
SOURCE
BMC Public Health;2007, Vol. 7 Issue 1, p7
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Background: Recent reports suggest an increase in sexually-transmitted hepatitis C infection among HIV-infected men who have sex with men (MSM) in European cities. We investigated whether current national surveillance systems in England and Wales (E&W) are able to monitor sexual transmission of hepatitis C infection among HIV-infected MSM. Methods: Routine laboratory reports of hepatitis C diagnoses and data from sentinel hepatitis C testing surveillance were matched to HIV diagnosis reports to determine: (i) the number of MSM diagnosed with HIV and hepatitis C (1996-2003); (ii) the number of HIV-diagnosed MSM tested for hepatitis C and found to be positive at sentinel sites (2003). Results: (i) Between 1996-2003, 38,027 hepatitis C diagnoses were reported; 25,938 (68%) were eligible for matching with HIV diagnoses. Thirty-one men (four in London) had both a HIV and hepatitis C diagnosis where the only risk was sex with another man. Numbers of "co-diagnosed" MSM increased from 0 in 1996 to 14 in 2003. The majority of MSM (22/31) tested hepatitis C positive after HIV diagnosis. (ii) Of 78,058 test results from sentinel hepatitis C testing sites in 2003, 67,712 (87%) were eligible for matching with HIV diagnoses. We identified 242 HIV-diagnosed MSM who did not inject drugs who tested for hepatitis C in 2003; 11 (4.5%) tested hepatitis C positive (95%CI: 2.3%-8.0%). Applying this percentage to all MSM seen for HIV-related care in E&W in 2003, an estimated 680 MSM living with diagnosed HIV would have tested positive for sexually-transmitted hepatitis C (95%CI: 346-1208). Conclusion: Matching routine laboratory reports of hepatitis C diagnoses with HIV diagnoses only identified 31 HIV infected MSM with sexually-transmitted hepatitis C infection. Clinical studies suggest that this is an underestimate. On the other hand, matching sentinel surveillance reports with HIV diagnoses revealed that in E&W in 2003 nearly 5% of HIV-diagnosed MSM tested hepatitis C positive where the only risk was sex with another man. Reports of sexually-transmitted hepatitis C infection were not confined to London. Enhanced surveillance is needed to monitor sexually-transmitted hepatitis C among HIV-infected MSM in E&W.
ACCESSION #
29361908

 

Related Articles

  • Virological Mechanisms in the Coinfection between HIV and HCV. Liberto, Maria Carla; Zicca, Emilia; Pavia, Grazia; Quirino, Angela; Marascio, Nadia; Torti, Carlo; Focà, Alfredo // Mediators of Inflammation;10/1/2015, Vol. 2015, p1 

    Due to shared transmission routes, coinfection with Hepatitis C Virus (HCV) is common in patients infected by Human Immunodeficiency Virus (HIV). The immune-pathogenesis of liver disease in HIV/HCV coinfected patients is a multifactorial process. Several studies demonstrated that HIV worsens the...

  • Prevalence of Hepatitis B and C Virus Infections in Children Infected with HIV. Toussi, Sima Shelly; Abadi, Jacobo; Rosenberg, Michael; Levanon, Daniela // Clinical Infectious Diseases;9/15/2007, Vol. 45 Issue 6, p795 

    We evaluated the prevalence and transmission mode of hepatitis B and C in an inner-city, pediatric cohort of human immunodeficiency virus (HIV)-infected persons, as well as the demographic characteristics of the cohort. Hepatitis B or C was found in 13 (5.8%) of 228 children. This analysis...

  • New International Coalition aims to expand Global access to HIV/AIDS treatment.  // Weekly Epidemiological Record;12/20/2002, Vol. 77 Issue 51, p438 

    Reports on the launching of the International HIV Treatment Access Coalition. Increase of access to antiretroviral drugs.

  • Positive Nutrition for HIV Infection and AIDS. Shevitz, Abby; Bell, Stacey J.; Armour Forse, R. // Nutrition in Clinical Care;Jan/Feb2000, Vol. 3 Issue 1, p54 

    Positive Nutrition for HIV Infection and AIDS provides straightforward and much-needed advice to patients and health care providers on a variety of topics in nutritional health related to HIV infection. Despite a huge volume of popular literature dedicated to HIV disease, there has been a lack...

  • NEWS IN BRIEF: KENTUCKY.  // Advocate;4/21/92, Issue 601, p29 

    Reports on the state senate's approval of a bill that would prescribe penalties for prostitution performed by people who know they are HIV-positive in Kentucky.

  • NEWS IN BRIEF: NEW YORK.  // Advocate;4/21/92, Issue 601, p29 

    Reports on the introduction of a measure in New York that would require public school administrators to warn parents of students in their districts if a student or school employee tests HIV-positive.

  • NEWS IN BRIEF: TENNESSEE.  // Advocate;4/21/92, Issue 601, p29 

    Reports on the Tennessee senate judiciary committee's approval of a measure that makes it a felony for HIV-positive people to knowingly place others at risk for exposure to HIV.

  • The Relationship between Ethnicity, Sex, Risk Group, and Virus Load in Human Immunodeficiency Virus Type 1 Antiretroviral-Naive Patients. Saul, Jacky; Erwin, Jo; Kulasegaram, Ranjababu; Peters, Barry S.; Sabin, Caroline A. // Journal of Infectious Diseases;5/15/2001, Vol. 183 Issue 10, p1518 

    Examines the relationships between ethnicity, sex, risk group and virus load in HIV type 1 antiretroviral-naive patients. Demographic and clinical characteristics of subjects; Virus load and CD4... lymphocyte counts in relation to different patient characteristics; Effects of selected...

  • CE/CME questions.  // AIDS Alert;Sep2008, Vol. 23 Issue 9, p107 

    A quiz concerning HIV/AIDS infection is presented.

Share

Other Topics