Validation and results of a questionnaire for functional bowel disease in out-patients

Mouzas, Ioannis A.; Fragkiadakis, Nikolaos; Moschandreas, Joanna; Karachristos, Andreas; Skordilis, Panagiotis; Kouroumalis, E.; Manousos, Orestes N.
January 2002
BMC Public Health;2002, Vol. 2 Issue 1, p8
Academic Journal
Background: The aim was to evaluate and validate a bowel disease questionnaire in patients attending an out-patient gastroenterology clinic in Greece. Methods: This was a prospective study. Diagnosis was based on detailed clinical and laboratory evaluation. The questionnaire was tested on a pilot group of patients. Interviewer-administration technique was used. One-hundred-and-forty consecutive patients attending the out-patient clinic for the first time and fifty healthy controls selected randomly participated in the study. Reliability (kappa statistics) and validity of the questionnaire were tested. We used logistic regression models and binary recursive partitioning for assessing distinguishing ability among irritable bowel syndrome (IBS), functional dyspepsia and organic disease patients. Results: Mean time for questionnaire completion was 18 min. In test-retest procedure a good agreement was obtained (kappa statistics 0.82). There were 55 patients diagnosed as having IBS, 18 with functional dyspepsia (Rome I criteria), 38 with organic disease. Location of pain was a significant distinguishing factor, patients with functional dyspepsia having no lower abdominal pain (p < 0.001). Significant factors distinguishing between IBS and functional dyspepsia were relief of pain by either antacids or defecation (19% vs 71% and 66% vs 0% respectively). Awakening from pain at night was also a factor distinguishing between IBS and organic disease groups (26% vs 61%, p < 0.01). Conclusions: This questionnaire for functional bowel disease is a valid and reliable instrument that can distinguish satisfactorily between organic and functional disease in an out-patient setting.


Related Articles

  • Self-Reported Abuse and Gastrointestinal Disease in Outpatients: Association with Irritable Bowel-Type Symptoms. Talley, Nicholas J.; Fett, Sara L.; Zinsmeister, Alan R. // American Journal of Gastroenterology;Mar1995, Vol. 90 Issue 3, p366 

    Objective: A link between functional bowel disease and sexual, physical, emotional, or verbal abuse remains controversial. We aimed to determine whether abuse is associated with functional bowel disease in outpatients. Methods: A consecutive sample of outpatients completed a validated...

  • Predictors of Self-reported Confidence Ratings for Adult Recall of Early Life Sun Exposure. Relova, Anne-Sharon; Marrett, Loraine D.; Klar, Neil; McLaughlin, John R.; Ashbury, Fredrick D.; Nishri, Diane; Theis, Beth // American Journal of Epidemiology;Jul2005, Vol. 162 Issue 2, p183 

    Use of self-reported confidence ratings may be an efficient method for assessing recall bias. In this exploratory application of the method, the authors examined the relation between case-control status and self-reported confidence ratings. In 2002 and 2003, melanoma cases (n = 141) and controls...

  • Test-retest reliability of ICECAP-A in the adult Danish population. Holst-Kristensen, Annette Willemoes; Fonager, Kirsten; Pedersen, Kjeld Møller // Quality of Life Research;Feb2020, Vol. 29 Issue 2, p547 

    Purpose: To investigate the test-retest reliability of Investigating Choice Experiments Capability measure for Adults (ICECAP-A) in the adult Danish population.Methods: The original English ICECAP-A was translated into Danish by forward-backwards translation using the...

  • An International Survey of the Use and Attitudes Regarding Alternative Medicine by Patients With Inflammatory Bowel Disease. Rawsthorne, Patricia; Shanahan, Fergus; Cronin, Neil C.; Anton, Peter A.; Löfberg, Robert; Bohman, Lena; Bernstein, Charles N. // American Journal of Gastroenterology;May1999, Vol. 94 Issue 5, p1298 

    OBJECTIVE: There is a perception of increasing and widespread use of alternative medicine for inflammatory bowel disease (IBD). We assessed the usage of alternative therapies among patients with IBD, whether there were similar or contrasting variables that were predictive of such use, and...

  • Validation of ICD-9-CM diagnostic codes for inflammatory bowel disease among veterans. Thirumurthi, Selvi; Chowdhury, Reezwana; Richardson, Peter; Abraham, Neena; Abraham, Neena S // Digestive Diseases & Sciences;Sep2010, Vol. 55 Issue 9, p2592 

    Background: Inflammatory bowel disease (IBD) is well described among young whites and less so among the elderly and non-whites. Population-level data is required to assess outcomes among minority groups.Aim: To validate diagnostic codes for IBD from the Department of...

  • Gastric Acid Suppression Is Associated with an Increased Risk of Adverse Outcomes in Inflammatory Bowel Disease. Shah, Rajesh; Richardson, Peter; Yu, Hong; Kramer, Jennifer; Hou, Jason Ken // Digestion;Apr2017, Vol. 95 Issue 3, p188 

    Background: The intestinal microbiota may influence inflammatory bowel disease (IBD) activity. Histamine 2 receptor antagonists (H2RAs) and proton pump inhibitors (PPIs) can alter the intestinal microbiota. The aim of this study was to assess the relationship between H2RAs, PPIs, and IBD-related...

  • Maternal Feeding Behavior and Child Acceptance of Food During Diarrhea, Convalescence, and Health in the Central Sierra of Peru. Bentley, Margaret E.; Stallings, Rebecca Y.; Fukumoto, Mary; Elder, John A. // American Journal of Public Health;Jan1991, Vol. 81 Issue 1, p43 

    Feeding patterns by mothers and child acceptance of food were measured in a Peruvian village to determine changes on days when children had diarrhea as compared to days of convalescence and health. Morbidity surveillance identified 40 children, aged 4-36 months, with diarrhea. Children were...

  • Association of labia! and/or palatine fissure with socioeconomic variables: a case-control study. Escoffié-Ramirez, Mauricio; Medina-Solís, Carlo Eduardo; Pontigo-Loyola, America Patricia; Acuña-González, Gladys; Casanova-Rosado, Juan Fernando; Colome-Ruiz, Gabriel Eduardo // Revista Brasileira de Saude Materno Infantil;jul-set2010, Vol. 10 Issue 3, p323 

    Objectives: to investigate the association between socioeconomic position and the presence of nonsyndromic cleft lip and/or palate (CLIP). Methods: a case-control study with 110 cases with CL/P matched by age and gender with 220 controls was carried out, the cases were selected from the...

  • Risk Factors for Enamel Fluorosis in a Nonfluoridated Population. Pendrys, David G.; Katz, Ralph V.; Morse, Douglas E. // American Journal of Epidemiology;1996, Vol. 143 Issue 8, p808 

    The purpose of this case-control investigation was to investigate the possible association between mild to moderate enamel fluorosis and exposure during early childhood to fluoride supplements, fluoride toothpaste, and/or infant formula use in nonfluoridated communities. Analysis was performed...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics