TITLE

Attitudes to antipsychotic drugs and their side effects: a comparison between general practitioners and the general population

AUTHOR(S)
Helbling, Josef; Ajdacic-Gross, Vladeta; Lauber, Christoph; Weyermann, Ruth; Burns, Tom; Rössler, Wulf
PUB. DATE
January 2006
SOURCE
BMC Psychiatry;2006, Vol. 6, p42
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Background: Attitudes towards antipsychotic medication play an important part in the treatment for schizophrenia and related disorders. We aimed measuring general practitioners' attitudes to antipsychotic drugs and their adverse side effects and comparing these with the attitudes of the general population. Methods: Analysis and comparison of two representative samples, one comprising 100 General Practitioners (GPs), the other 791 individuals randomly selected from the general population. The setting was the German speaking cantons of Switzerland. Results: General practitioners have significantly more positive attitudes towards anti-psychotic drugs than the general public. They reject widespread prejudices about the use of anti-psychotic medication significantly more than the general population. In particular the risk of dependency was assessed as 'low' by GP's (80%), in contrast to only 18% of the general population sample. In no instance did a majority of the GPs advise not tolerating any of the 10 possible adverse effects presented in this study. This is in marked contrast to the general population sample, where a majority recommended discontinuation for movement disorder (63%), strong tremor (59%), risk of dependency (55%) and feelings of unrest (54%). Conclusion: As well as effective management of side-effects being a vital aspect of patient and carer education, prescribing doctors need to be aware that their mentally ill patients are likely to be confronted with extremely negative public attitudes towards antipsychotic medication and with strong pressures to stop taking their medication in the event of side-effects.
ACCESSION #
29323769

 

Related Articles

  • Reduction in psychotic symptoms as a predictor of patient satisfaction with antipsychotic medication in schizophrenia: Data from a randomized double-blind trial. Gharabawi, Georges M.; Greenspan, Andrew; Rupnow, Marcia F. T.; Kosik-Gonzalez, Colette; Bossie, Cynthia A.; Young Zhu; Kalali, Amir H.; Awad, A. George // BMC Psychiatry;2006, Vol. 6, p45 

    Background: Patient satisfaction with antipsychotic treatment is important. Limited evidence suggests that satisfaction is associated with symptom improvement and compliance. Predictors of patient satisfaction with antipsychotic medication were examined in a study of patients with a recent...

  • Time to discontinuation of atypical versus typical antipsychotics in the naturalistic treatment of schizophrenia. Ascher-Svanum, Haya; Baojin Zhu; Faries, Douglas; Landbloom, Ron; Swartz, Marvin; Swanson, Jeff // BMC Psychiatry;2006, Vol. 6, p8 

    Background: There is an ongoing debate over whether atypical antipsychotics are more effective than typical antipsychotics in the treatment of schizophrenia. This naturalistic study compares atypical and typical antipsychotics on time to all-cause medication discontinuation, a recognized index...

  • zotepine.  // Royal Society of Medicine: Medicines;2002, p580 

    This article presents information on zotepine, an antipsychotic drug which can be used for the treatment of schizophrenia. It is taken orally.

  • Improvement of Prefrontal Brain Function in Endogenous Psychoses Under Atypical Antipsychotic Treatment. Ehlis, Ann-Christine; Herrmann, Martin J.; Pauli, Paul; Stoeber, Gerald; Pfuhlmann, Bruno; Fallgatter, Andreas J. // Neuropsychopharmacology;Aug2007, Vol. 32 Issue 8, p1669 

    Typical and atypical antipsychotics are thought to exert their effects on different neurotransmitter pathways with specific action of atypical compounds on the prefrontal cortex, but studies directly investigating the effect of those drugs on neurophysiological measures of prefrontal brain...

  • The Effect of Fluphenazine Enanthate on Chronic and Relapsing Schizophrenia. Lowther, John // British Journal of Psychiatry;Jun69, Vol. 115 Issue 523, p691 

    The article examines the effect of fluphenazine enanthate on chronic and relapsing schizophrenia. According to the author, fluphenazine enanthate is used in conjunction with an active rehabilitation program to schizopherinic subjects. Treatment is set while the patient is in the hospital, and...

  • Effects of long-term treatment with antipsychotics on serum leptin levels. Herrán, Andrés; García-Unzueta, María Teresa; Amado, José Antonio; de la Maza, María Teresa; Álvarez, Concepción; Vázquez-Barquero, José Luis // British Journal of Psychiatry;Jul2001, Vol. 179, p59 

    Background Abnormal regulation of the adipocyte-derived hormone leptin could play a role in body weight gain induced by antipsychotics. Aims To study the effects of long-term antipsychotic treatment on leptin levels in patients with schizophrenia. Method Serum leptin levels were determined in 59...

  • Schizophrenia and quality of life: a one-year follow-up in four EU countries. Kovess-Masféty, Viviane; Xavier, Miguel; Kustner, Berta Moreno; Suchocka, Agnieszka; Sevilla-Dedieu, Christine; Dubuis, Jacques; Lacalmontie, Elisabeth; Pellet, Jacques; Roelandt, Jean-Luc; Walsh, Dermot // BMC Psychiatry;2006, Vol. 6, p39 

    Background: This article systematically monitors the quality of life (QOL) of patients with schizophrenia from seven different sites across four European countries: France, Ireland, Portugal and Spain. Methods: A one-year prospective cohort study was carried out. Inclusion criteria for patients...

  • Clozapine, agranulocytosis, and benign ethnic neutropenia. Rajagopal, S. // Postgraduate Medical Journal;Sep2005, Vol. 81 Issue 959, p545 

    Focuses on Clozapine, which is effective in schizophrenia. Information on severe adverse effect of clozapine; Association of clozapine with increased risk of eosinophilia; Focus on the mechanism of clozapine induced agranulocytosis.

  • Suicidality and second generation anytipsychotics in schizophrenia patients: a case-controlled retrospective study during a 5-year period. Barak, Y.; Mirecki, I.; Knobler, H. Y.; Natan, Z.; Aizenberg, D. // Psychopharmacology;2004, Vol. 175 Issue 2, p215 

    Discusses a study which assessed in a large cohort of schizophrenia patients the effects of exposure to second-generation antipsychotics on suicidality of patients suffering from schizophrenia or schizoaffective disorder. Situation wherein suicide is more likely to occur; Range of estimates of...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics