Exploratory analysis of obsessive compulsive symptom dimensions in children and adolescents: a Prospective follow-up study

Delorme, Richard; Bille, Arnaud; Betancur, Catalina; Mathieu, Flavie; Chabane, Nadia; Mouren-Simeoni, Marie Christine; Leboyer, Marion
January 2006
BMC Psychiatry;2006, Vol. 6, p1
Academic Journal
Background: Recent statistical approaches based on factor analysis of obsessive compulsive (OC) symptoms in adult patients have identified dimensions that seem more effective in symptom-based taxonomies and appear to be more stable over time. Although a phenotypic continuum from childhood to adulthood has been hypothesized, no factor analytic studies have been performed in juvenile patients, and the stability of OC dimensions in children and adolescents has not been assessed. Methods: This study was designed to perform an exploratory factor analysis of OC symptoms in a sample of children and adolescents with OC disorder (OCD) and to investigate the course of factors over time (mean follow-up period: four years). Results: We report for the first time that four symptom dimensions, remarkably similar to those previously described in adults, underlined the heterogeneity of OC symptoms in children and adolescents. Moreover, after follow-up, the symptom dimensions identified remained essentially unmodified. The changes observed concerned the intensity of dimensions rather than shifts from one dimension to another. Conclusion: These findings reinforce the hypothesis of a phenotypic continuum of OC symptoms from childhood to adulthood. They also strengthen the interest for investigating the clinical, neurobiological and genetic heterogeneity of OCD using a dimension-based approach.


Related Articles

  • Does This Child Have Appendicitis? Bundy, David G.; Byerley, Julie S.; Liles, E. Allen; Perrin, Eliana M.; Katznelson, Jessica; Rice, Henry E. // JAMA: Journal of the American Medical Association;7/25/2007, Vol. 298 Issue 4, p438 

    This article presents a study to assess the precision and accuracy of symptoms of appendicitis in children so that physicians have clearer signs for diagnosing the disease in children who present with lower abdominal pain. The goal was to discover indicators of appendicitis to speed up a...

  • Infant with chronic bilateral retroauricular tumefaction (2009: 3a).  // European Radiology;Mar2009, Vol. 19 Issue 3, p787 

    The article presents a case of a 3-year-old boy with bilateral retroauricular tumefaction who was treated with several antibiotics and whose disease will be diagnosed by readers.

  • Pediatric emergency: Assessing gut pain. Boxel, Ann Van; Puhl, Philip M.; Boyd, Leslie // RN;Apr2001, Vol. 64 Issue 4, p38 

    Discusses how emergency department (ED) personnel can assess pediatric patients with gastrointestinal (GI) disease and abdominal pain. Symptoms of GI disease in children; Conditions that could result in intestinal perforation, peritonitis or necrosis of the bowel; Chronic GI conditions in...

  • Experiencia de diez años de la enterocolitis neutropénica en la Unidad de Terapia Intensiva Pediátrica del Instituto Nacional de Pediatría. Muñoz-Ramírez, Mireya; Márquez-González, Horacio; Zárate-Castañón, Patricia; Márquez-Aguirre, Martha Patricia // Acta Pediatrica de Mexico;sep/oct2014, Vol. 35 Issue 5, p381 

    Conclusiones: este estudio es de carácter exploratorio y permite comparar la epidemiología mundial con la de la Unidad de Terapia Intensiva Pediátrica del Instituto Nacional de Pediatría. Neutropenic enterocolitis (NEC) is a disease characterized by an inflammatory process with...

  • Recurrent Abdominal Pain in Children. Liebman, William M. // Clinical Pediatrics;Feb1978, Vol. 17 Issue 2, p149 

    The clinical pattern of 119 children with recurrent abdominal pain, located most commonly in the periumbilical region, revealed no distinct features. The most common associated symptoms were pallor, tiredness and anorexia. The most important socioenvironmental and behavioral factors were marital...

  • CT Scans on Children: Is This a Problem? Miller, Alvin A. // Clinical Pediatrics;Apr2008, Vol. 47 Issue 3, p220 

    The article examines the benefits and risks of computed tomography (CT scan) on children with trauma or abdominal symptoms in the U.S. It is evident that CT scan has become a very common procedure in the evaluation of children because of its significant contribution to the improvement of...

  • Bilateral carpal tunnel syndrome in a child with type 1 diabetes mellitus. Duru, Nilgun Selcuk; Acar, Hurtan; Semih Ayta; Elevli, Murat // Neurology India;Jan2010, Vol. 58 Issue 1, p136 

    The article focuses on the importance to conduct a diagnosis of bilateral carpal tunnel syndrome (CTS) among children and adolescents to be able to alleviate symptoms and improve living conditions in Turkey. The disease has been found to be extremely uncommon in pediatric age group. However, the...

  • Obstructive Upper Airway Problems and Primary Enuresis Nocturna Relationship in Pediatric Patients: Reciprocal Study. Aydil, Utku; İşeri, Elvan; Kızıl, Yusuf; Bodur, Şahin; Ceylan, Alper; Uslu, Sabri // Journal of Otolaryngology -- Head & Neck Surgery;Apr2008, Vol. 37 Issue 2, p235 

    Objective: To determine the relationship between primary enuresis nocturna (PEN) and obstructive upper airway problems (OUAPs). Design: Prospective, descriptive study. Setting: Tertiary care academic medical centre. Methods: Two groups of patients were included in the study. Newly diagnosed...

  • Commentary: More valid criteria may be needed. Little, Paul // BMJ: British Medical Journal (International Edition);12/6/2003, Vol. 327 Issue 7427, p1327 

    Comments on the research of Zwart et al on the use of antibiotics in children. Discussion of the Centor criteria used in evaluating unwell children; View that criteria based on immunological evidence of infection need to be developed; The issue of whether antibiotics predict benefit.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics