Absence of cross-tolerance and the situational specificity of tolerance

Siegel, Shepard; Kim, Joseph A
January 2000
Palliative Medicine;Jan2000, Vol. 14 Issue 1, p75
Academic Journal
Suggests that the disruption of tolerance in a patient who showed tolerance to morphine but no tolerance to fentanyl is a demonstration of the situational specificity of tolerance. Factors modulating morphine tolerance; Experimental demonstrations of the role of interoceptive stimuli in the display of tolerance to opioids.


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