TITLE

Multifactorial experimental design and the transitivity of ratios with spotted DNA microarrays

AUTHOR(S)
Townsend, Jeffrey P.
PUB. DATE
January 2003
SOURCE
BMC Genomics;2003, Vol. 4, p41
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Background: Multifactorial experimental designs using DNA microarrays are becoming increasingly common, but the extent of the transitivity of cDNA microarray expression measurements across multiple samples has yet to be explored. Results: A strong correlation between direct and transitive inference for significantly differentially expressed genes is demonstrated, using subsets of a dye-swap loop design. Conclusions: In experimental design, opportunities for transitive inference should be exploited, while always ensuring that comparisons of greatest interest comprise direct hybridizations.
ACCESSION #
28834600

 

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics