TITLE

A wearable hemofilter for continuous ambulatory ultrafiltration

AUTHOR(S)
Gura, V.; Ronco, C.; Nalesso, F.; Brendolan, A.; Beizai, M.; Ezon, C.; Davenport, A.; Rambod, E.
PUB. DATE
February 2008
SOURCE
Kidney International;Feb2008, Vol. 73 Issue 4, p497
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Ultrafiltration is effective for treating fluid overload, but there are no suitable machines for ambulatory treatment. This study summarizes the use of a light-weight wearable continuous ambulatory ultrafiltration device consisting of a hollow fiber hemofilter, a battery operated pulsatile pump, and two micropumps to control heparin administration and ultrafiltration. Six volume-overloaded patients underwent ultrafiltration for 6 h with treatment discontinued in one patient due to a clotted catheter. Blood flow averaged 116 ml min−1, the ultrafiltration rate ranged from 120–288 ml h−1 with about 150 mmol of sodium removed. Blood pressure, pulse, and biochemical parameters remained stable with no significant hemolysis or complications. Our data show that the wearable hemofilter appears to be safe, effective, and practical for patients. This device could have a major impact on the quality of life of fluid-overloaded patients with heart failure. Additional studies will be needed to confirm these initial promising results.Kidney International (2008) 73, 497–502; doi:10.1038/sj.ki.5002711; published online 5 December 2007
ACCESSION #
28724605

 

Related Articles

  • Improved Permeate Flux of PVDF Ultrafiltration Membrane Containing PVDF-g-PHEA Synthesized via ATRP. Kwang-Mo Kim; Sahng Hyuck Woo; Ju Sung Lee; Hyun Sic Park; Jinwon Park; Byoung Ryul Min // Applied Sciences (2076-3417);2015, Vol. 5 Issue 4, p1992 

    Polyvinylidene fluoride (PVDF) ultrafiltration (UF) membrane combined with polyvinylidene fluoride-graft-2-hydroxyethyl acrylate (PVDF-g-PHEA) was fabricated via non-solvent induced phase separation (NIPS). In this study, PVDF-g-PHEA was synthesized via atom transfer radical polymerization...

  • Model-based control of MF/UF filtration processes: pilot plant implementation and results. Busch, J.; Marquardt, W. // Water Science & Technology;2009, Vol. 59 Issue 9, p1713 

    Membrane micro- and ultrafiltration processes are widespread in water and wastewater treatment applications. Owing to the complex filtration mechanisms and the few available measurement information, they are typically operated using simple control approaches. However, two negative consequences...

  • CARRESS-HF: Ultrafiltration Not Superior to Pharmacologic Therapy in the Treatment of Acute Heart Failure. Buckley, Rita // MD Conference Express;Dec2012, p24 

    The article discusses the findings from the Cardiorenal Rescue Study in Acute Decompensated Heart Failure (CARRESS-HF) trial by Bradley A. Bart. The study aims to test whether ultrafiltration was superior to stepped pharmacologic therapy for the treatment of patients with acute decompensated...

  • Impact of Two Types of Sodium and Ultra Filtration Profiles on Systolic and Diastolic Blood Pressure in patients during Hemodialysis. Ghafourifard, M.; Rafieian, M.; Shahgholian, N.; Mortazavi, M. // HAYAT;2010, Vol. 16 Issue 1, p5 

    Background & Aim: Intradialytic hypotension is the most frequent complication in patients receiving haemodialysis (HD). This complication not only contributes to the illness of the patients, but also decreases the efficacy of the HD. So, hypotension prevention is a major challenge for medical...

  • Preparation of Polyvinylidene Fluoride (PVDF) Hollow Fiber Hemodialysis Membranes. Qinglei Zhang; Xiaolong Lu; Lihua Zhao // Membranes;Mar2014, Vol. 4 Issue 1, p81 

    In this study, the polyvinylidene fluoride (PVDF) hollow fiber hemodialysis membranes were prepared by non-solvent induced phase separation (NIPS). The influences of PVDF membrane thickness and polyethylene glycol (PEG) content on membrane morphologies, pore size, mechanical and permeable...

  • Heart Failure and Tachycardia: A Worrisome Combination. Grais, Martin; Miller, Albert J. // Cortlandt Forum;11/25/2002, Vol. 15 Issue 11, p25 

    Focuses on the treatment of the patient with heart failure and sinus tachycardia. Examination on the medical history of the patient; Observation of the blood pressure; Importance of physical examination.

  • Microfiltration runs wide open. Wright, Andrew G // ENR: Engineering News-Record;09/21/98, Vol. 241 Issue 11, p34 

    Presents information on microfiltration. Success of the microfiltration market; Process of microfiltration and ultrafiltration; History of microfilters and ultrafilters.

  • Associations of a facility level decrease in dialysate sodium concentration with blood pressure and interdialytic weight gain. Hla Thein; Imad Haloob; Mark R. Marshall // Nephrology Dialysis Transplantation;Sep2007, Vol. 22 Issue 9, p2630 

    Background. Dialysate [Na+] is often overlooked as a contributor to hypertension in patients on haemodialysis (HD). We report observational experience with a facility level decrease in dialysate [Na+] from 141 mmol/l to 138 mmol/l, in the absence of concurrent change with respect...

  • Evaluation of Risk Factors for Congestive Heart Failure.  // Annals of Internal Medicine;1/7/2003, Vol. 138 Issue 1, p22 

    Evaluates the risk factors of congestive heart failure. Characteristics of congestive heart failure; Cause of congestive heart failure; Methods to measure blood pressure.

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics