Review: Prophylactic use of granulocyte colony-stimulating factor reduces febrile neutropenia and short-term mortality in cancer

January 2008
ACP Journal Club;Jan/Feb2008, Vol. 148 Issue 1, p7
Academic Journal
The article presents a clinical study that evaluates whether the primary prophylactic use of granulocyte colony-stimulating factor (G-CSF) reduces febrile neutropenia and early mortality in adult patients with cancer. The study showed that the use of G-CSF reduced febrile neutropenia and short-term mortality during the chemotherapy period. It is also showed that the G-CSF increases dose intensity of delivered chemotherapy, but increases bone pain.


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