TITLE

Review: Tricyclic antidepressants, anticonvulsants, opioids, and capsaicin cream are effective treatments for diabetic neuropathy

PUB. DATE
January 2008
SOURCE
ACP Journal Club;Jan/Feb2008, Vol. 148 Issue 1, p2
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article presents a clinical study that evaluates the effectiveness of treatments for painful diabetic neuropathy. A randomized, double-blind, placebo-controlled study was conducted. The study indicated that the tricyclic antidepressants, traditional and newer-generation anti-convulsants, opioid, duloxerine and capsaicin cream are effective short-term therapy for painful diabetic neuropathy in adults.
ACCESSION #
28694418

 

Related Articles

  • The Best Pain Relievers for Diabetic Neuropathy.  // HealthFacts;Jul2007, Vol. 32 Issue 7, p6 

    The article discusses a study on drugs that offer effective short-term pain relief for people with diabetic neuropathy. The Hong Kong team led by Man-chun Wong reviewed all relevant studies and found that an older class of antidepressants called tricyclic antidepressants and an older class of...

  • Efficacy of antiepileptic drugs (AEDs) in the treatment of neuropathic pain varies according to the type of pain.  // Drugs & Therapy Perspectives;Apr2008, Vol. 24 Issue 4, p17 

    Neuropathic pain is a complex disorder and exists in different forms (e.g. diabetic neuropathy, postherpetic neuralgia). Treatment usually includes the use of anti- epileptic agents (AEDs), but rarely provides complete pain relief First-line options are carbamazepine and perhaps oxcarbazepine...

  • Current Concepts in the Management of Diabetic Polyneuropathy. Ziegler, Dan // Current Diabetes Reviews;May2011, Vol. 7 Issue 3, p208 

    Approximately one in three people with diabetes is affected by diabetic distal symmetric sensorimotor polyneuropathy (DSPN), which represents a major health problem as it may present with excruciating neuropathic pain and is responsible for substantial morbidity, increased mortality and impaired...

  • Medical Treatment of Symptomatic Diabetic Neuropathy. Boulton, Andrew J. M. // Immunology, Endocrine & Metabolic Agents - Medicinal Chemistry;Feb2007, Vol. 7 Issue 1, p79 

    Diabetic peripheral neuropathy affects up to 50% of older type 2 diabetic patients: at any time, up to 50% of patients will experience painful or uncomfortable symptoms, some of whom will require symptomatic therapy. The first step in management is to exclude other causes of neuropathy and...

  • Questionnaire on neuropathic pain: a European neurologist survey. Sommer, C.; Geis, C.; Haanpää, M.; Serra, J.; Tan, E.; Cruccu, G. // Neurological Sciences;Jun2007, Vol. 28 Issue 3, p136 

    A survey was conducted among European neurologists to obtain information on their interest in, knowledge on, and practice in the treatment of neuropathic pain. A simple questionnaire with 11 closed and one open question was distributed at national meetings, via e-mail lists of national...

  • Chapter 5: Diabetic and postherpetic neuropathic pain.  // Fast Facts: Chronic Pain;2007, p41 

    Chapter 5 of the book "Fast Facts: Chronic Pain," by M. Soledad Cepeda, Michael J. Cousins and Daniel B. Carr is presented. It examines the effect of diabetic neuropathy on autonomic and peripheral nervous systems. It discusses the possible therapies for postherpetic neuralgia. It analyzes the...

  • COMMENTARY: Review: Tricyclic antidepressants, anticonvulsants, opioids, and capsaicin cream are effective treatments for diabetic neuropathy. Murad, M. Hassan; Smith, Steven A. // ACP Journal Club;Jan/Feb2008, Vol. 148 Issue 1, p2 

    The author comments on the study concerning the efficacy of drugs for diabetic neuropathy. He asserts that the finding that the tricyclic antidepressants, anticonvulsants, opioids and capsaicin are more effective than placebo in reducing pain was overestimated due to publication bias. He...

  • Painful Diabetic Neuropathy: A Management-Centered Review. Huizinga, Mary Margaret; Peltier, Amanda // Clinical Diabetes;Winter2007, Vol. 25 Issue 1, p6 

    The article reviews the diagnosis, prevention and management of painful diabetic neuropathy (PDN). It also discusses commonly used agents including duloxetine and pre-gabalin and their effective dose ranges, titration schemes, contraindications and recommended monitoring. Strict glycemic control...

  • A Cost-Utility Comparison of Four First-Line Medications in Painful Diabetic Neuropathy. O'Connor, Alec B.; Noyes, Katia; Holloway, Robert G. // PharmacoEconomics;2008, Vol. 26 Issue 12, p1045 

    Background: Painful diabetic neuropathy is common and adversely affects patients' quality of life and function. Several treatment options exist, but their relative efficacy and value are unknown. Objective: To determine the relative efficacy, costs and cost effectiveness of the first-line...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics