TITLE

Inhibition of NKCC1 may be beneficial in sepsis

AUTHOR(S)
Jayaraman, B.
PUB. DATE
January 2008
SOURCE
Thorax;Jan2008, Vol. 63 Issue 1, p34
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article summarizes a study by M. Nguyen and colleagues on the benefits of Na+K+Cl cotransporter (NKCC1) inhibition in sepsis. The study found that NKCC1 contributes to changes in pulmonary vascular permeability during inflammation and loss of NKCC1 expression shows a protective effect against hypothermic sepsis and bacteremia.
ACCESSION #
28681896

 

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