TITLE

Low adherence to colonoscopy in the screening of first-degree relatives of patients with colorectal cancer

AUTHOR(S)
Bujanda, Luis; Sarasqueta, Cristina; Zubiaurre, Leire; Cosme, Angel; Muñoz, Carmen; Sánchez, Araceli; Martín, Cristina; Tito, Ilucia; Piñol, Virginia; Castells, Antoni; Llor, Xavier; Xicola, Rosa M.; Pons, Elisenda; Clofent, Juan; de Castro, Maria L.; Cuquerella, Jaime; Medina, Enrique; Gutierrez, Ana; Arenas, Juan I.; Jover, Rodrigo
PUB. DATE
December 2007
SOURCE
Gut;Dec2007, Vol. 56 Issue 12, p1714
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Background: Colonoscopy is one of the methods of choice for screening relatives of patients with colorectal cancer. Objective: To evaluate the rate of adherence to colonoscopy in first-degree relatives of patients with colorectal cancer and describe the lesions found. Methods: A prospective, cross-sectional, multicentre, nationwide study was conducted. The study population was composed of first-degree relatives of patients with colorectal cancer selected randomly from the EPICOLON study. Seventy-four index patients were included. These had 342 living first-degree relatives (parents, siblings and children), of whom 281 were interviewed. Results: The adherence rate was 38% (107/281). Adherence was greater in families with a higher degree of familial aggregation for colorectal cancer (88.9% for Amsterdam vs 33.3% for Bethesda and sporadic cancer; p<0.05), an index patient aged under 65 years (60% for patients <65 years vs 32.9% for patients ⩾65 years; p<0.05) and an index patient who was female (46.2% for women vs 31% for men; p=0.28). Adherence was also greater in relatives under 65 years (54% in patients <65 years vs 18% in patients ⩾65 years; p=0.05), in female relatives (49% in female relatives vs 27.3% in male relatives; p<0.05) and in siblings and children (40% in siblings and children vs 13% in parents; p<0.05). Lesions were found in 26% (28/107) of the study population. Nine (8.4%) individuals had a total of 18 advanced lesions. Conclusions: These results indicate that adherence to colonoscopy in our population of first-degree relatives was low. The adherence was more frequently associated with a higher degree of familial aggregation, a relative age of under 65 years, a sibling or offspring relationship, and female sex.
ACCESSION #
28105577

 

Related Articles

  • Methodological approaches to population based research of screening procedures in the presence of selection bias and exposure measurement error: colonoscopy and colorectal cancer outcomes in Ontario. Jacob, Binu J.; Sutradhar, Rinku; Moineddin, Rahim; Baxter, Nancy N.; Urbach, David R. // BMC Medical Research Methodology;2013, Vol. 13 Issue 1, p1 

    Background: The study describes the methodological challenges encountered in an observational study estimating the effectiveness of colonoscopy in reducing colorectal cancer (CRC) incidence and mortality. Methods: Using Ontario provincial administrative data, we conducted a population-based...

  • Hudson Valley Hospital offering virtual colonoscopy.  // Westchester County Business Journal;12/15/2003, Vol. 42 Issue 50, p18 

    Reports on the availability of virtual colonoscopy, a screening for the detection of colorectal cancer, at Hudson Valley Hospital Center in Cortlandt Manor, New York. Cause of cancer related deaths; Features of the virtual colonoscopy.

  • Cost-Containment Redux: Time for Physicians to Engage. Kravitz, Richard // JGIM: Journal of General Internal Medicine;Sep2012, Vol. 27 Issue 9, p1093 

    An introduction is presented in which the author discusses various reports within the issue on topics including one on the survey to over 1,200 primary care providers concerning the efficacy of colonoscopy, one on colorectal cancer (CRC) screening and one on the impact of delayed or absent...

  • ATL>A population-based, community estimate of total colon examination: the impact on compliance with screening for colorectal cancer. Schoen, Robert E.; Weissfeld, Joel L.; Trauth, Jeanette M.; Ling, Bruce S.; Hayran, Mutlu // American Journal of Gastroenterology;Feb2002, Vol. 97 Issue 2, p446 

    OBJECTIVE:Colorectal cancer screening is underutilized. Total colon examination (TCE), such as with colonoscopy, can have a significant effect on the measured compliance with screening, as colonoscopy may be able to be performed as infrequently as once every 10 yr. In a population-based survey...

  • Gastrointestinal Endoscopy.  // Biomedical Market Newsletter;3/21/2012, Vol. 21, p1 

    The article offers information a health survey conducted by the Mount Sinai School of Medicine in New York researchers which revealed the impact of increased colonoscopic pressure on the quality of colon cancer screening.

  • COLORECTAL CANCER PREVENTION.  // American Journal of Gastroenterology;Sep2005 Supplement 2, Vol. 100, pS383 

    The article presents abstracts of research papers related to colorectal cancer prevention. They include "The Finding of Heme Positive Stool Should Prompt Investigation, Despite Prior Normal Colonoscopy," "Attending a Pre-Procedural Education Session Does Not Improve Compliance with Screening...

  • Independent Nurse: Screening could see waiting times increase.  // GP: General Practitioner;9/16/2005, p72 

    The article reports that the national colorectal cancer screening programme in Great Britain will increase colonoscopies by 28 percent, possibly leading to longer waiting times. The researchers assessed the impact of a pilot colorectal cancer screening programme using data from seven hospitals...

  • Colorectal Screening after Polypectomy: A National Survey Study of Primary Care Physicians. Boolchand, Vikram; Olds, Gregory; Singh, Joseph; Singh, Pankaj; Chak, Amitabh; Cooper, Gregory S. // Annals of Internal Medicine;11/7/2006, Vol. 145 Issue 9, p654 

    Background: Recommendations by primary care physicians for colorectal screening after polypectomy will influence rates of colonoscopy in open-access systems that do not require consultation by a gastroenterologist before colonoscopy. Objective: To determine the surveillance recommendations of...

  • Recommendations Raise Workload Issues for Colon Cancer Screening. Twombly, Renee // JNCI: Journal of the National Cancer Institute;3/3/2004, Vol. 96 Issue 5, p348 

    Examines why few countries have adopted colon cancer screening programs. Various tests for colon cancer screening in the United States; Burden that extensive colon cancer screening places on colonoscopy services; Great Britain's launch of a mass colorectal screening program; Lack of colorectal...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics